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Circulation. 1979;60:1104-1113

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Circulation, Vol 60, 1104-1113, Copyright © 1979 by American Heart Association


ARTICLES

Cross-sectional echocardiography. I. Analysis of mathematic models for quantifying mass of the left ventricle in dogs

HL Wyatt, MK Heng, S Meerbaum, JD Hestenes, JM Cobo, RM Davidson and E Corday

Cross-sectional echocardiography was used to quantify left ventricular mass noninvasively in 21 dogs. Short- and long-axis cross-sectional images of the left ventricle were reproducibly traced at endocardial and epicardial borders during stop-motion video-tape replay. We used area, length and diameter measurements to calculate left ventricular mass by seven mathematic models, including the standard formulas used with M-mode echocardiography and cineangiography. Calculated mass was compared with excised weight of the left ventricle by regression and percent error analyses. Formulas using short-axis areas and long-axis length resulted in higher correlation coefficients (0.94--0.95) and lower mean errors (6--7%) than for standard formulas. Since short-axis areas account for regional left ventricular irregularities, noninvasive quantification of left ventricular mass by cross-sectional echocardiography in dogs is most accurate with formulas using short- axis areas.


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