Circulation, Vol 57, 870-879, Copyright © 1978 by American Heart Association
AE Becker, RH Anderson, D Durrer and HJ Wellens
Clinicopathological correlations were made on the hearts from seven
patients known to have exhibited electrocardiographic evidence of the
Wolff-Parkinson-White syndrome. In each case, clinical and pathological
investigations were conducted independently, neither group of investigators
having knowledge of the other's results. In all seven hearts, the entire
atrioventricular junctions were serially sectioned. Accessory
atrioventricular connections were predicted in all seven cases following
electrocardiographic investigation. Connections were identified
histopathologically in four hearts in the predicted site. In another case
two connections were identified, one being considered responsible for the
pre-excitation. In the sixth case a right lateral connection was
anticipated, but only accessory nodo-ventricular fibers were identified
following histopathologic studies. In the final case, a posterior septal
connection was predicted but the entire septum had fibrosed following
previous operation. These findings are discussed in the light of the
investigative techniques used, the theories of pre- excitation and the
embryogenetic mechanisms producing accessory atrioventricular connections.
ARTICLES
The anatomical substrates of wolff-parkinson-white syndrome. A clinicopathologic correlation in seven patients
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