Circulation, Vol 57, 1022-1025, Copyright © 1978 by American Heart Association
WD Edwards, DS Leaf and JE Edwards
Among 119 cases of fatal dissecting aneurysm of the aorta, exclusive of
those iatrogenically caused or associated with arachnodactyly or aortic
stenosis, there were observed 11 cases of congenital bicuspid aortic valve
(9%). The ages ranged from 17 to 69 years, five of the patients being 29
years old or younger. Among the latter, three had coarctation of the aorta
and one had Turner's syndrome without coarctation. In one of the older
patients, aortic insufficiency was present. Hypertension was either
established or inferred from cardiac weight in 73% of the cases. In each
case, cystic medial necrosis of the aorta was present. Prolapse of valves
other than the aortic was observed in 45% of the cases with bicuspid aortic
valve. Compared to an estimated incidence of bicuspid aortic valve of about
1 to 2% in the population, the high incidence among subjects with
dissecting aneurysm suggests a causative relationship between bicuspid
aortic valve and aortic dissecting aneurysm.
ARTICLES
Dissecting aortic aneurysm associated with congenital bicuspid aortic valve
This article has been cited by other articles:
 |
|
 |
|
  S. K. Tiryakioglu, O. Tiryakioglu, T. Turan, and E. Kumbay Aortic dissection due to sildenafil abuse Interactive CardioVascular and Thoracic Surgery, July 1, 2009; 9(1): 141 - 143. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Carlson and M Silberbach Dissection of the aorta in Turner syndrome: two cases and review of 85 cases in the literature BMJ Case Reports, July 1, 2009; 2009(jul01_1): bcr0620091998 - bcr0620091998. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. Silberbach Bicuspid aortic valve and thoracic aortic aneurysm: toward a unified theory. J. Am. Coll. Cardiol., June 16, 2009; 53(24): 2296 - 2297. [Full Text] [PDF]
|
|
|
|
 |
|
 A. O. Caglayan and M. Dundar Inherited diseases and syndromes leading to aortic aneurysms and dissections Eur. J. Cardiothorac. Surg., June 1, 2009; 35(6): 931 - 940. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M. Tadros, M. D. Klein, and O. M. Shapira Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve: Pathophysiology, Molecular Biology, and Clinical Implications Circulation, February 17, 2009; 119(6): 880 - 890. [Full Text] [PDF]
|
|
|
|
|
|
F. Ozaslan, T. Wittlinger, N. Monsefi, T. Bouhmidi, S. Theres, M. Doss, G. Wimmer-Greinecker, and A. Moritz Long-term follow-up of supra-annular pulmonary autograft aortic root replacement in patients with bicuspid aortic valve Eur. J. Cardiothorac. Surg., September 1, 2008; 34(3): 583 - 588. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. S. Fazel, H. R. Mallidi, R. S. Lee, M. P. Sheehan, D. Liang, D. Fleischman, R. Herfkens, R. S. Mitchell, and D. C. Miller The aortopathy of bicuspid aortic valve disease has distinctive patterns and usually involves the transverse aortic arch. J. Thorac. Cardiovasc. Surg., April 1, 2008; 135(4): 901 - 907.e2. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. E. David Aortic Valve Repair and Aortic Valve Sparing Operations Card. Surg. Adult, January 1, 2008; 3(2008): 935 - 948. [Full Text]
|
|
|
|
 |
|
 L. G. Svensson, N. T. Kouchoukos, D. C. Miller, J. E. Bavaria, J. S. Coselli, M. A. Curi, H. Eggebrecht, J. A. Elefteriades, R. Erbel, T. G. Gleason, et al. Expert Consensus Document on the Treatment of Descending Thoracic Aortic Disease Using Endovascular Stent-Grafts Ann. Thorac. Surg., January 1, 2008; 85(1_Supplement): S1 - S41. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Carlson and M Silberbach Dissection of the aorta in Turner syndrome: two cases and review of 85 cases in the literature J. Med. Genet., December 1, 2007; 44(12): 745 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. D. Etz, T. M. Homann, D. Silovitz, D. Spielvogel, C. A. Bodian, M. Luehr, G. DiLuozzo, K. A. Plestis, and R. B. Griepp Long-Term Survival After the Bentall Procedure in 206 Patients With Bicuspid Aortic Valve Ann. Thorac. Surg., October 1, 2007; 84(4): 1186 - 1194. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-H. Sievers and C. Schmidtke A classification system for the bicuspid aortic valve from 304 surgical specimens J. Thorac. Cardiovasc. Surg., May 1, 2007; 133(5): 1226 - 1233. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Aicher, C. Urbich, A. Zeiher, S. Dimmeler, and H.-J. Schafers Endothelial Nitric Oxide Synthase in Bicuspid Aortic Valve Disease Ann. Thorac. Surg., April 1, 2007; 83(4): 1290 - 1294. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Goland, L. S.C. Czer, M. A. De Robertis, J. Mirocha, R. M. Kass, G. P. Fontana, W. Chang, and A. Trento Risk Factors Associated With Reoperation and Mortality in 252 Patients After Aortic Valve Replacement for Congenitally Bicuspid Aortic Valve Disease Ann. Thorac. Surg., March 1, 2007; 83(3): 931 - 937. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Majumdar, M. Yagubyan, G. Sarkar, M. E. Bolander, and T. M. Sundt III Bicuspid aortic valve and ascending aortic aneurysm are not associated with germline or somatic homeobox NKX2-5 gene polymorphism in 19 patients J. Thorac. Cardiovasc. Surg., June 1, 2006; 131(6): 1301 - 1305. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Cripe, G. Andelfinger, L. J. Martin, K. Shooner, and D. W. Benson Bicuspid aortic valve is heritable J. Am. Coll. Cardiol., July 7, 2004; 44(1): 138 - 143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Muir, M. H.D. Danton, and G. Campalani Acute aortic dissection following non-structural failure of a prosthetic aortic valve Interactive CardioVascular and Thoracic Surgery, December 1, 2003; 2(4): 450 - 451. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Picchi, M. Focardi, G. Capannini, and S. Mondillo Aortic Dissection After Aortic Valve Replacement: A Case Report and Literature Review Angiology, November 1, 2003; 54(6): 715 - 719. [Abstract] [PDF]
|
|
|
|
 |
|
 C A Warnes Bicuspid aortic valve and coarctation: two villains part of a diffuse problem Heart, September 1, 2003; 89(9): 965 - 966. [Full Text] [PDF]
|
|
|
|
|
|
F.-X. Schmid, K. Bielenberg, A. Schneider, A. Haussler, A. Keyser, and D. Birnbaum Ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve: involvement and clinical relevance of smooth muscle cell apoptosis and expression of cell death-initiating proteins Eur. J. Cardiothorac. Surg., April 1, 2003; 23(4): 537 - 543. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. T. Nkomo, M. Enriquez-Sarano, N. M. Ammash, L. J. Melton III, K. R. Bailey, V. Desjardins, R. A. Horn, and A. J. Tajik Bicuspid Aortic Valve Associated With Aortic Dilatation: A Community-Based Study Arterioscler. Thromb. Vasc. Biol., February 1, 2003; 23(2): 351 - 356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. E. David Aortic Valve Repair and Aortic Valve-Sparing Operations Card. Surg. Adult, January 1, 2003; 2(2003): 811 - 824. [Full Text]
|
|
|
|
|
|
M. Bauer, M. Pasic, R. Meyer, N. Goetze, U. Bauer, H. Siniawski, and R. Hetzer Morphometric analysis of aortic media in patients with bicuspid and tricuspid aortic valve Ann. Thorac. Surg., July 1, 2002; 74(1): 58 - 62. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Niitsuma, Y. Takahara, Y. Sudo, and H. Nakano Acute type A aortic dissection associated with an aortic annular abscess Ann. Thorac. Surg., December 1, 2001; 72(6): 2136 - 2137. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Langer, T. Graeter, N. Nikoloudakis, D. Aicher, O. Wendler, and H.-J. Schafers Valve-preserving aortic replacement: Does the additional repair of leaflet prolapse adversely affect the results? J. Thorac. Cardiovasc. Surg., August 1, 2001; 122(2): 270 - 277. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-J. Schafers, F. Langer, D. Aicher, T. P. Graeter, and O. Wendler Remodeling of the aortic root and reconstruction of the bicuspid aortic valve Ann. Thorac. Surg., August 1, 2000; 70(2): 542 - 546. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. M. Sundt III, B. N. Mora, M. R. Moon, M. S. Bailey, M. K. Pasque, and W. A. Gay Jr Options for repair of a bicuspid aortic valve and ascending aortic aneurysm Ann. Thorac. Surg., May 1, 2000; 69(5): 1333 - 1337. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Ward Clinical significance of the bicuspid aortic valve Heart, January 1, 2000; 83(1): 81 - 85. [Full Text] [PDF]
|
|
|
|
|
|
S Nistri, M D Sorbo, M Marin, M Palisi, R Scognamiglio, and G Thiene Aortic root dilatation in young men with normally functioning bicuspid aortic valves Heart, July 1, 1999; 82(1): 19 - 22. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Bonderman, E. Gharehbaghi-Schnell, G. Wollenek, G. Maurer, H. Baumgartner, and I. M. Lang Mechanisms Underlying Aortic Dilatation in Congenital Aortic Valve Malformation Circulation, April 27, 1999; 99(16): 2138 - 2143. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. P. Sybert Cardiovascular Malformations and Complications in Turner Syndrome Pediatrics, January 1, 1998; 101 (1): e11 - e11. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. E. David, A. Omran, G. Webb, H. Rakowski, S. Armstrong, and Z. Sun GEOMETRIC MISMATCH OF THE AORTIC AND PULMONARY ROOTS CAUSES AORTIC INSUFFICIENCY AFTER THE ROSS PROCEDURE J. Thorac. Cardiovasc. Surg., November 1, 1996; 112(5): 1231 - 1239. [Abstract] [Full Text]
|
|
|
|
 |
|
 W. I. Schievink and B. Mokri Familial Aorto-Cervicocephalic Arterial Dissections and Congenitally Bicuspid Aortic Valve Stroke, October 1, 1995; 26(10): 1935 - 1940. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. Lindsay JR, J. Rosenberg, J. W. Ross, and J. M. Garcia Anuloaortic Ectasia as a Late Complication Following Repair of Coarctation of the Aorta Vascular and Endovascular Surgery, September 1, 1986; 20(5): 288 - 292. [Abstract] [PDF]
|
|
|
|
 |
|
 C. R. Fikar, J. A. Amrhein, J. P. Harris, and E. R. Lewis Dissecting Aortic Aneurysm in Childhood and Adolescence: Case Report and Literature Review Clinical Pediatrics, September 1, 1981; 20(9): 578 - 583. [Abstract] [PDF]
|
|