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Circulation, Vol 56, 273-278, Copyright © 1977 by American Heart Association
G Gerstenblith, J Frederiksen, FC Yin, NJ Fortuin, EG Lakatta and ML Weisfeldt
Echocardiograms were performed on 105 male participants in the National
Institutes on Aging's volunteer Longitudinal Study Program. All subjects
(25--84 years of age) were physically active and had no evidence of
hypertension or cardiovascular disease. Measurements were made of the
initial diastolic (E-F) slope of the anterior mitral valve leaflet, the
aortic and left ventricular cavity dimensions, and the thickness of the
posterior left ventricular wall. Fractional shortening of the minor
semi-axis of the left ventricle and the velocity of circumferential fiber
shortening were also determined. It was found that increasing age
correlated with a decrease mitral valve E-F slope and increased aortic root
diameter and left ventricular wall thickness. Aging did not affect left
ventricular cavity dimension, fractional shortening of the minor semi-axis,
and velocity of circumferential fiber shortening. These findings suggest
that aging in the normal male is associated with altered left ventricular
diastolic filling, increased aortic root diameter and left ventricle
hypertrophy but little change in contractile ability in the resting state.
ARTICLES
Echocardiographic assessment of a normal adult aging population
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