1 From the Cardiopulmonary Laboratory, U. S. Public Health Service Hospital, Staten Island, New York.
Studies have shown that in patients with paroxysmal supraventricular tachycardia (SVT), spontaneous or stimulated atrial premature depolarizations (APD) falling within a specific portion of the relative refractory period of the atrioventricular (A-V) conduction system initiate SVT. The present study was designed to determine whether the A-V nodal conduction delay these APDs exhibit, or their coupling interval, is essential for the initiation of SVT. Multiple episodes of SVT were initiated and terminated by single APDs in four patients with a history of paroxysmal SVT. The atria were then paced at numerous fixed rates in excess of the spontaneous sinus rate. In each patient, at atrial rates where progressive A-V nodal conduction delay occurred from beat to beat (Wenckebach cycles), a specific degree of A-V nodal conduction delay always resulted in atrial reentry or SVT. Although the atrial coupling interval was considerably longer during Wenckebach cycles initiating SVT than for single APDs resulting in the arrhythmia, the prolongation of A-V nodal conduction was identical. Independent of atrial coupling interval, a requisite degree of A-V nodal conduction delay always resulted in atrial echoes or SVT. This supports the conclusion that SVT results from atrial reentry via the A-V node.
Submitted on October 26, 1970
© 1971 American Heart Association, Inc.
The Essential Role of Atrioventricular Conduction Delay in the Initiation of Paroxysmal Supraventricular Tachycardia
Key Words: Paroxysmal atrial tachycardia A-V nodal conduction A-V refractory periods Atrial echoes Atrial reentry His bundle electrogram A-V Wenckebach cycles Atrial pacing
Accepted on January 25, 1971
This article has been cited by other articles:
![]() |
C. M. Tracy, M. Akhtar, J. P. DiMarco, D. L. Packer, H. H. Weitz, M. A. Creager, D. R. Holmes Jr, G. Merli, G. P. Rodgers, C. M. Tracy, et al. American College of Cardiology/American Heart Association 2006 Update of the Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion: A Report of the American College of Cardiology/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training Developed in Collaboration With the Heart Rhythm Society J. Am. Coll. Cardiol., October 3, 2006; 48(7): 1503 - 1517. [Full Text] [PDF] |
||||
![]() |
K. M. Heinroth, K. Kattenbeck, I. Stabenow, H.-J. Trappe, and P. Weismuller Multiple AV nodal pathways in patients with AV nodal reentrant tachycardia -- more common than expected? Europace, January 1, 2002; 4(4): 375 - 382. [Abstract] [PDF] |
||||
![]() |
C. M. Tracy, M. Akhtar, J. P. DiMarco, D. L. Packer, H. H. Weitz, W. L. Winters, J. L. Achord, A. W. Boone, J. W. Hirshfeld Jr, B. H. Lorell, et al. American College of Cardiology/American Heart Association Clinical Competence Statement on invasive electrophysiology studies, catheter ablation, and cardioversion: A report of the american college of cardiology/american heart association/american college of physicians-american society of internal medicine task force on clinical competence J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1725 - 1736. [Full Text] [PDF] |
||||
![]() |
C. M. Tracy, M. Akhtar, J. P. DiMarco, D. L. Packer, H. H. Weitz, W. L. Winters, J. L. Achord, A. W. Boone, J. W. Hirshfeld Jr, B. H. Lorell, et al. American College of Cardiology/American Heart Association Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion : A Report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence Circulation, October 31, 2000; 102(18): 2309 - 2320. [Full Text] [PDF] |
||||
![]() |
P. Loh, J. M. T. de Bakker, M. Hocini, B. Thibault, R. N. W. Hauer, and M. J. Janse Reentrant Pathway During Ventricular Echoes Is Confined to the Atrioventricular Node : High-Resolution Mapping and Dissection of the Triangle of Koch in Isolated, Perfused Canine Hearts Circulation, September 21, 1999; 100(12): 1346 - 1353. [Abstract] [Full Text] [PDF] |
||||
![]() |
H Hatzinikolaou, L-M Rodriguez, J L R M Smeets, C Timmermans, G Vrouchos, G Grecas, and H J J Wellens Isoprenaline and inducibility of atrioventricular nodal re-entrant tachycardia Heart, February 1, 1998; 79(2): 165 - 168. [Abstract] [Full Text] |
||||
![]() |
J. Sra, M. Jazayeri, A. Natale, A. Dhala, Z. Blanck, S. Deshpande, C. Maglio, S. Bremner, and M. Akhtar Termination of Atrioventricular Nodal Reentrant Tachycardia by Premature Stimulation From Ablating Catheter : A Reliable Guide to Identify Site for Slow-Pathway Ablation Circulation, February 15, 1995; 91(4): 1095 - 1100. [Abstract] [Full Text] |
||||
![]() |
L. Littmann, J. Tenczer, and T. Fenyvesi Atrioventricular Nodal Reentrant Paroxysmal Supraventricular Tachycardia Arch Intern Med, January 1, 1984; 144(1): 129 - 131. [Abstract] [PDF] |
||||
![]() |
D. G. BENDITT, E. L. C. PRITCHETT, W. M. SMITH, and J. J. GALLAGHER Ventriculoatrial Intervals: Diagnostic Use in Paroxysmal Supraventricular Tachycardia Ann Intern Med, August 1, 1979; 91(2): 161 - 166. [Abstract] [PDF] |
||||
![]() |
M. E. JOSEPHSON and J. A. KASTOR Supraventricular Tachycardia: Mechanisms and Management Ann Intern Med, September 1, 1977; 87(3): 346 - 358. [Abstract] [PDF] |
||||
![]() |
D. R. STEMPLE, J. W. FITZGERALD, and R. A. WINKLE Benign Slow Paroxysmal Atrial Tachycardia Ann Intern Med, July 1, 1977; 87(1): 44 - 48. [Abstract] [PDF] |
||||
![]() |
L. LESSER and P. F. WALTER Atrial Tachycardia in Acute Myocardial Infarction Ann Intern Med, May 1, 1977; 86(5): 582 - 583. [Abstract] [PDF] |
||||
![]() |
D. Wu and P. Denes Mechanisms of Paroxysmal Supraventricular Tachycardia Arch Intern Med, March 1, 1975; 135(3): 437 - 442. [Abstract] [PDF] |
||||
![]() |
K. M. Rosen, R. G. Dhingra, and P. Denes Diagnostic Evaluation of Arrhythmic Disorders: Clinical Application of His Bundle Electrography JAMA, July 1, 1974; 229(1): 63 - 64. [Abstract] [PDF] |
||||
![]() |
J. A. Kastor Electrical Disorders of the Heart JAMA, May 14, 1973; 224(7): 1031 - 1033. [Abstract] [PDF] |
||||
![]() |
B. N. GOLDREYER Intracardiac Electrocardiography in the Analysis and Understanding of Cardiac Arrhythmias Ann Intern Med, July 1, 1972; 77(1): 117 - 136. [Abstract] [PDF] |
||||
|
Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 1971 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |