1 From the Cardiovascular Division, Department of Medicine, Peter Bent Brigham Hospital and Harvard Medical School, Boston, Massachusetts.
Coronary angiography, cine left ventriculography, and the cardiovascular hemodynamics of 24 patients with left bundle branch block were studied. Seven patients were found to have significant coronary artery disease, always severe. Five had cardiomyopathy and seven had valvular disease. Only those with coronary artery disease or cardiomyopathy had abnormal left ventricular contraction patterns. The onset of left ventricular contraction was delayed in the patients with left bundle branch block, but the period of isovolumic contraction was normal in those without severe underlying disease. Left axis deviation in addition to left bundle branch block did not imply more frequent coronary atherosclerosis.
Submitted on March 30, 1970
© 1971 American Heart Association, Inc.
Left Bundle Branch Block
Etiologic, Hemodynamic, and Ventriculographic Considerations
Key Words: Coronary angiography Left ventriculography Electromechanical delay
Accepted on October 26, 1970
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