1 From the Department of Physiology, Gymnastikoch idrottshögskolan, Stockholm, and the Department of Clinical Physiology, University of Göteborg, Göteborg, Sweden.
Blood lipids, red cell volume, heart volume, dynamic spirometry, electrocardiograms made at rest and during exercise, and maximal oxygen uptake were determined in 29 former athletes 45 to 70 years old. The subjects had been very successful competitors in endurance events before the age of 30, but for at least 10 years preceding this study had been sedentary. Maximal oxygen uptake averaged 40 ml/kg/min which is 20% higher than that of sedentary middle-aged men but 25% lower than that of still active athletes of the same ages. Vital capacity, forced expiratory volume, and maximal voluntary ventilation showed normal values. Heart volume was large in relation to maximal oxygen uptake and was of the same magnitude as in still active athletes. Red cell volume was also large in relation to maximal oxygen uptake, but normal in relation to the body weight. Cholesterol in serum averaged 260 mg/100 ml. Values for neutral fat averaged 1.6 mM, which was higher than that for still active athletes. In the athletes still active, the frequency of S-T changes was as common as in unselected healthy old men but in the former athletes the frequency was reduced. This was also true for the frequency of right bundle-branch block, ST-junction elevation and high T waves.
© 1968 American Heart Association, Inc.
Physiological Analysis of Middle-Aged and Old Former Athletes
Comparison with Still Active Athletes of the Same Ages
Key Words: Maximal oxygen uptake • Heart volume • Red cell volume • ECG during exercise • Blood lipids in former endurance athletes • Dynamic spirometry
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
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|
|
|
|
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|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
I. Thune, I. Njolstad, M.-L. Lochen, and O. H. Forde Physical Activity Improves the Metabolic Risk Profiles in Men and Women: The Tromso Study Arch Intern Med, August 10, 1998; 158(15): 1633 - 1640. [Abstract] [Full Text]
|
|
|
|
|
|
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|
|
|
|
|
|
B. Hedblad, M. Ogren, S.-O. Isacsson, and L. Janzon Reduced Cardiovascular Mortality Risk in Male Smokers Who Are Physically Active: Results From a 25-Year Follow-up of the Prospective Population Study Men Born in 1914 Arch Intern Med, April 28, 1997; 157(8): 893 - 899. [Abstract] [PDF]
|
|
|
|
|
|
L.-G. Persson, K. Lindstrom, H. Lingfors, and C. Bengtsson A study of men aged 33-42 in Habo, Sweden with special reference to cardiovascular risk factors: Design, health profile and characteristics of participants and non-participants Scand J Public Health, December 1, 1994; 22(4): 264 - 272. [Abstract] [PDF]
|
|
|
|
 |
|
 W. M. Bortz II Disuse and Aging JAMA, September 10, 1982; 248(10): 1203 - 1208. [Abstract] [PDF]
|
|
|
|
|
|
J. T. Salonen, J. Tuomilehto, and P. Puska The Relation of Physical Activity Changes to Changes in Serum Cholesterol and Body Weight in a Three-Year Follow-up of Population Sample Scand J Public Health, January 1, 1981; 9(3): 109 - 117. [Abstract] [PDF]
|
|