1 From the Vascular Section, Clinical Investigation Unit, St. Boniface General Hospital, and the Department of Physiology, University of Manitoba, Winnipeg, Canada.
Measurements were carried out in 146 limbs with angiographically documented arterial occlusive disease (AOD) and in 85 limbs without AOD. Ankle systolic pressure (AP) was equal to or higher than brachial systolic pressure in limbs without AOD. It was below 82% of the brachial in all limbs with complete occlusion, usually below 50% in those with multiple occlusions, and above 50% in limbs with single block. AP was below normal in 19 of 25 limbs with severe and in five of nine with mild stenosis. All limbs with complete occlusion and 14 of 16 with stenosis had abnormal pressures in the thigh. The foot-to-peak time (CT) and the width of pulse waves at half amplitude (WD) were related to heart rate in normal limbs. Considering the heart rate, the majority of limbs with AOD had abnormally prolonged CT and WD. Normal pressures and pulse waves were found together in only two limbs with stenosis and symptoms. The findings indicate that pressures and pulse waves provide a sensitive method for diagnosis and follow-up of patients with AOD.
© 1968 American Heart Association, Inc.
Indirect Systolic Pressures and Pulse Waves in Arterial Occlusive Disease of the Lower Extremities
Key Words: Ankle systolic blood pressure Popliteal pulse waves Width of pulse waves Pedal pulse waves Crest time Arterial stenosis Intermittent claudication Thigh systolic blood pressure Peripheral vascular disease
This article has been cited by other articles:
![]() |
P. Sritara, C. Sritara, M. Woodward, S. Wangsuphachart, F. Barzi, B. Hengprasith, and T. Yipintsoi Prevalence and Risk Factors of Peripheral Arterial Disease in a Selected Thai Population Angiology, November 1, 2007; 58(5): 572 - 578. [Abstract] [PDF] |
||||
![]() |
R. Stein, I. Hriljac, J. L Halperin, S. M Gustavson, V. Teodorescu, and J. W Olin Limitation of the resting ankle-brachial index in symptomatic patients with peripheral arterial disease Vascular Medicine, February 1, 2006; 11(1): 29 - 33. [Abstract] [PDF] |
||||
![]() |
K. W. Beach D. Eugene Strandness, Jr, MD, and the Revolution in Noninvasive Vascular Diagnosis: Part 1: Foundations J. Ultrasound Med., March 1, 2005; 24(3): 259 - 272. [Full Text] [PDF] |
||||
![]() |
D. Roy, J. Quiles, R. Sharma, M. Sinha, P. Avanzas, D. Gaze, and J. C. Kaski Ischemia-Modified Albumin Concentrations in Patients with Peripheral Vascular Disease and Exercise-Induced Skeletal Muscle Ischemia Clin. Chem., September 1, 2004; 50(9): 1656 - 1660. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Arboix, M. Tarruella, L. Garcia-Eroles, M. Oliveres, C. Miquel, M. Balcells, and C. Targa Ischemic stroke in patients with intermittent claudication: a clinical study of 142 cases Vascular Medicine, February 1, 2004; 9(1): 13 - 17. [Abstract] [PDF] |
||||
![]() |
K. Malanin, V. K. Havu, and P. J. Kolari Dynamics of Cutaneous Laser Doppler Flux with Concentration of Moving Blood Cells and Blood Cell Velocity in Legs with Venous Ulcers and in Healthy Legs Angiology, January 1, 2004; 55(1): 37 - 42. [Abstract] [PDF] |
||||
![]() |
C.-H. Tseng Prevalence and Risk Factors of Peripheral Arterial Obstructive Disease in Taiwanese Type 2 Diabetic Patients Angiology, May 1, 2003; 54(3): 331 - 338. [Abstract] [PDF] |
||||
![]() |
M. Kallio, C. Forsblom, P.-H. Groop, L. Groop, and M. Lepantalo Development of New Peripheral Arterial Occlusive Disease in Patients With Type 2 Diabetes During a Mean Follow-Up of 11 Years Diabetes Care, April 1, 2003; 26(4): 1241 - 1245. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. W. Gardner and P. S. Montgomery Impaired Balance and Higher Prevalence of Falls in Subjects With Intermittent Claudication J. Gerontol. A Biol. Sci. Med. Sci., July 1, 2001; 56(7): M454 - 458. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. W Gardner, L. Forrester, and G. V Smith Altered gait profile in subjects with peripheral arterial disease Vascular Medicine, February 1, 2001; 6(1): 31 - 34. [Abstract] [PDF] |
||||
![]() |
A. Fronek, S. Oglevie, B. Curran, and K. Fronek Combination of pressure and velocity parameters in the non-invasive diagnosis of aorto-iliac disease Vascular Medicine, May 1, 1999; 4(2): 77 - 81. [Abstract] [PDF] |
||||
![]() |
A. R. Yataco, A. W. Gardner, and A. W. Gardner Acute Reduction in Ankle/Brachial Index Following Smoking in Chronic Smokers with Peripheral Arterial Occlusive Disease Angiology, May 1, 1999; 50(5): 355 - 360. [Abstract] [PDF] |
||||
![]() |
M. McGrae McDermott, S. Mehta, and P. Greenland Exertional Leg Symptoms Other Than Intermittent Claudication Are Common in Peripheral Arterial Disease Arch Intern Med, February 22, 1999; 159(4): 387 - 392. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Malanin, P. Vilkko, and P. J. Kolari Venoarteriolar Response to Experimental Venous Hypertension in Legs with Chronic Venous Insufficiency and in Healthy Legs, Measured Using a Double-Wavelength Laser Doppler Technique Angiology, October 1, 1998; 49(10): 729 - 733. [Abstract] [PDF] |
||||
![]() |
S. R. McGee and E. J. Boyko Physical Examination and Chronic Lower-Extremity Ischemia: A Critical Review Arch Intern Med, June 22, 1998; 158(12): 1357 - 1364. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Malanin, P. Vilkko, and P. J. Kolari Blood Flux and Venoarteriolar Response of the Skin in Legs with Chronic Venous Insufficiency Measured at Two Different Depths by Using a Double-Wavelength Laser Doppler Technique Angiology, June 1, 1998; 49(6): 441 - 446. [Abstract] [PDF] |
||||
![]() |
R. B. McLafferty, G. L. Moneta, L. M. Taylor Jr, and J. M. Porter Ability of Ankle-Brachial Index to Detect Lower-Extremity Atherosclerotic Disease Progression Arch Surg, August 1, 1997; 132(8): 836 - 841. [Abstract] [PDF] |
||||
![]() |
M. Catalano, E. Perilli, G. Carzaniga, G. Scandale, and M. Carotta Arterial Damage, Triglycerides, Apolipoprotein, and Lp-(a) Values in PVD Patients Clinical and Applied Thrombosis/Hemostasis, April 1, 1997; 3(2): 104 - 109. [Abstract] [PDF] |
||||
![]() |
P. Abraham, B. Desvaux, D. Colin, G. Leftheriotis, and J.-L. Saumet Heart Rate-Corrected Ankle-to-Arm Index in the Diagnosis of Moderate Lower Extremity Arterial Disease Angiology, August 1, 1995; 46(8): 673 - 677. [Abstract] [PDF] |
||||
![]() |
M. Ogren, B. Hedblad, S.-O. Isacsson, L. Janzon, G. Jungquist, and S.-E. Lindell Ten year cerebrovascular morbidity and mortality in 68 year old men with asymptomatic carotid stenosis BMJ, May 20, 1995; 310(6990): 1294 - 1298. [Abstract] [Full Text] |
||||
![]() |
P. Rubba, G. Leccia, F. Faccenda, B. De Simone, L. Carbone, P. Pauciullo, O. Vaccaro, and M. Mancini Diabetes Mellitus and Localizations of Obliterating Arterial Disease of the Lower Limbs Angiology, April 1, 1991; 42(4): 296 - 301. [Abstract] [PDF] |
||||
![]() |
N. S. Angelides Continuous Infusion Treatment with Pentoxifylline in Patients with Severe Peripheral Vascular Occlusive Disease Angiology, August 1, 1986; 37(8): 555 - 564. [Abstract] [PDF] |
||||
![]() |
L. Janzon, S.-E. Bergentz, B. F. Ericsson, M. Hanson, and S.-E. Lindell Leg Blood Flow in Intermittent Claudication A Comparison Between Non Insulin Dependent Diabetics and Non Diabetics Angiology, November 1, 1984; 35(11): 724 - 728. [Abstract] [PDF] |
||||
![]() |
S. M. Giulini, S. Bonardelli, A. Bartoli, M. Floriani, and G. Tiberio Value of Doppler Multi-Level Segmental Pressure Index in the Diagnosis and Hemodynamic Characterization of Totally Occlusive Aorto-Iliac-Femoro-Popliteal Lesions Angiology, October 1, 1984; 35(10): 633 - 640. [Abstract] [PDF] |
||||
![]() |
I. Oliva and K. Roztocil Toe Pulse Wave Analysis in Obliterating Atherosclerosis Angiology, September 1, 1983; 34(9): 610 - 619. [Abstract] [PDF] |
||||
![]() |
S. A. Carter Arterial Auscultation in Peripheral Vascular Disease JAMA, October 9, 1981; 246(15): 1682 - 1686. [Abstract] [PDF] |
||||
![]() |
U. K. Franzeck, E. F. Bernstein, and A. Fronek The Effect of Sensing Site on the Limb Segmental Blood Pressure Determination Arch Surg, July 1, 1981; 116(7): 912 - 916. [Abstract] [PDF] |
||||
![]() |
N.S. Angelides Isolated Profunda Femoris Artery Occlusion: The Mechanism of Thigh Claudication Studied by 99mTc Muscle Clearance from the Thigh and Calf Angiology, June 1, 1981; 32(6): 379 - 387. [PDF] |
||||
![]() |
S. A. Carter Finger Systolic Pressures and Skin Temperatures in Severe Raynaud's Syndrome: The Relationship to Healing of Skin Lesions and the Use of Oral Phenoxybenzamine Angiology, May 1, 1981; 32(5): 298 - 310. [Abstract] [PDF] |
||||
![]() |
D. L. Clement and R. Claeys Diagnostic Performance of Segmental Plethysmography and Doppler Ultrasound in Obliterating Vascular Diseases in the Lower Limbs Angiology, April 1, 1980; 31(4): 272 - 282. [PDF] |
||||
![]() |
S. A. Carter Effect of Age, Cardiovascular Disease, and Vasomotor Changes on Transmission of Arterial Pressure Waves Through the Lower Extremities Angiology, August 1, 1978; 29(8): 601 - 616. [Abstract] [PDF] |
||||
![]() |
F. Mahler, L. Koen, K. H. Johansen, E. F. Bernstein, and A. Fronek Postocclusion and Postexercise Flow Velocity and Ankle Pressures in Normals and Marathon Runners Angiology, December 1, 1976; 27(12): 721 - 729. [PDF] |
||||
![]() |
D.S. Sumner and D.E. Strandness Applications of Ultrasound To the Study of Arteriosclerosis Obliterans Angiology, February 1, 1975; 26(2): 187 - 198. [PDF] |
||||
![]() |
J. S.T. Yao Exercise Testing Using Doppler Ultrasound and Xenon Clearance Techniques Angiology, January 1, 1975; 26(7): 528 - 533. [PDF] |
||||
![]() |
K. W. Johnston and V. V. Kakkar Noninvasive Measurement of Systolic Pressure Slope: A Reliable Index of the Presence of Peripheral Arterial Occlusive Disease Arch Surg, January 1, 1974; 108(1): 52 - 56. [Abstract] [PDF] |
||||
![]() |
J. S. T. Yao New Techniques in Objective Arterial Evaluation Arch Surg, April 1, 1973; 106(4): 600 - 604. [Abstract] [PDF] |
||||
![]() |
A. Bollinger, F. Mahler, and A. Gruentzig Peripheral Hemodynamics in Patients With Coarcta Tion, Normotensive and Hypertensive Arterio Sclerosis Obliterans of the Lower Limbs Angiology, June 1, 1971; 22(6): 354 - 363. [PDF] |
||||
![]() |
W. Delius and U. Erikson Correlation Between Angiographic and Hemodynamic Findings in Occlusions of Arteries of the Extremities Vascular and Endovascular Surgery, December 1, 1969; 3(4): 201 - 210. [PDF] |
||||
![]() |
S. A. Carter Clinical Measurement of Systolic Pressures in Limbs With Arterial Occlusive Disease JAMA, March 10, 1969; 207(10): 1869 - 1874. [Abstract] [PDF] |
||||
|
Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 1968 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |