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(Circulation. 2007;116:2203-2215.)
© 2007 American Heart Association, Inc.

Advances in Interventional Cardiology

Endovascular Therapies for Peripheral Arterial Disease

An Evidence-Based Review

Christopher J. White, MD; William A. Gray, MD

From the Department of Cardiology (C.J.W.), Ochsner Clinic Foundation, New Orleans, La, and Endovascular Services (W.A.G.), Center for Interventional Vascular Therapy, Columbia University Medical Center, New York, NY.

Correspondence to Christopher J. White, MD, Chairman, Department of Cardiology, Ochsner Clinic Foundation, 1514 Jefferson Hwy, New Orleans, LA 70121-2483. E-mail cwhite{at}ochsner.org

Peripheral arterial disease is one manifestation of systemic atherosclerosis. The prevalence of peripheral arterial disease increases with the age of the population. It is important to remember the significant association of coincident coronary artery disease, which is the major cause of mortality in these patients. Remarkable technological advances in the past decade, along with patient preference, have shifted revascularization strategies from traditional open surgical approaches toward lower-morbidity percutaneous endovascular treatments. The availability of stents, more than any other advance, has fueled the growth of catheter-based procedures by improving the safety, durability, and predictability of percutaneous revascularization.

Key Words: claudication • angioplasty • stents • angiogenesis • peripheral vascular diseases

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