Circulation. 2005;112:3149-3156
doi: 10.1161/CIRCULATIONAHA.104.531558
doi: 10.1161/CIRCULATIONAHA.104.531558
(Circulation. 2005;112:3149-3156.)
© 2005 American Heart Association, Inc.
Imaging |
New Noninvasive Method for Assessment of Left Ventricular Rotation
Speckle Tracking Echocardiography
From the Department of Cardiology (T.H.-V., T.E., E.L., H.I., O.A.S.), Rikshospitalet University Hospital; the Department of Circulation and Medical Imaging (J.C., B.H.A., H.T.), Norwegian University of Science and Technology, Trondheim; and the Department of Radiology (H.-J.S.), Rikshospitalet University Hospital, Oslo, Norway; and the Department of Cardiology (B.D.R., J.A.C.L.), Johns Hopkins University, Baltimore, Md.
Correspondence to Otto A. Smiseth, Department of Cardiology, Rikshospitalet University Hospital, N-0027 Oslo, Norway. E-mail Otto.Smiseth{at}rikshospitalet.no
Received February 23, 2004; revision received August 9, 2005; accepted August 10, 2005.
Background— Left ventricular (LV) torsion is due to oppositely directed apical and basal rotation and has been proposed as a sensitive marker of LV function. In the present study, we introduce and validate speckle tracking echocardiography (STE) as a method for assessment of LV rotation and torsion.
Methods and Results— Apical and basal rotation by STE was measured from short-axis images by automatic frame-to-frame tracking of gray-scale speckle patterns. Rotation was calculated as the average angular displacement of 9 regions relative to the center of a best-fit circle through the same regions. As reference methods we used sonomicrometry in anesthetized dogs during baseline, dobutamine infusion, and apical ischemia, and magnetic resonance imaging (MRI) tagging in healthy humans. In dogs, the mean peak apical rotation was –3.7±1.2° (±SD) and –4.1±1.2°, and basal rotation was 1.9±1.5° and 2.0±1.2° by sonomicrometry and STE, respectively. Rotations by both methods increased (P<0.001) during dobutamine infusion. Apical rotation by both methods decreased during left anterior descending coronary artery occlusion (P<0.007), whereas basal rotation was unchanged. In healthy humans, apical rotation was –11.6±3.8° and –10.9±3.3°, and basal rotation was 4.8±1.7° and 4.6±1.3° by MRI tagging and STE, respectively. Torsion measurement by STE showed good correlation and agreement with sonomicrometry (r=0.94, P<0.001) and MRI (r=0.85, P<0.001).
Conclusions— The present study demonstrates that regional LV rotation and torsion can be measured accurately by STE, suggesting a new echocardiographic approach for quantification of LV systolic function.
Key Words: echocardiography • ventricles • torsion • magnetic resonance imaging • rotation
This article has been cited by other articles:
 |
|
 |
|
  E. Donal, C. Bergerot, H. Thibault, L. Ernande, J. Loufoua, L. Augeul, M. Ovize, and G. Derumeaux Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study Eur J Echocardiogr, December 1, 2009; 10(8): 914 - 921. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. A. Popescu, C. C. Beladan, A. Calin, D. Muraru, D. Deleanu, M. Rosca, and C. Ginghina Left ventricular remodelling and torsional dynamics in dilated cardiomyopathy: reversed apical rotation as a marker of disease severity Eur J Heart Fail, October 1, 2009; 11(10): 945 - 951. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Bertini, N. A. Marsan, V. Delgado, R. J. van Bommel, G. Nucifora, C. J. W. Borleffs, G. Boriani, M. Biffi, E. R. Holman, E. E. van der Wall, et al. Effects of cardiac resynchronization therapy on left ventricular twist. J. Am. Coll. Cardiol., September 29, 2009; 54(14): 1317 - 1325. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. N. Shivu, K. Abozguia, T. T. Phan, I. Ahmed, R. Weaver, P. Narendran, M. Stevens, and M. Frenneaux Increased Left Ventricular Torsion in Uncomplicated Type 1 Diabetic Patients: The role of coronary microvascular function Diabetes Care, September 1, 2009; 32(9): 1710 - 1712. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-J. Nesser, V. Mor-Avi, W. Gorissen, L. Weinert, R. Steringer-Mascherbauer, J. Niel, L. Sugeng, and R. M. Lang Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: comparison with MRI Eur. Heart J., July 1, 2009; 30(13): 1565 - 1573. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Ferferieva, P. Claus, K. Vermeulen, C. Missant, M. Szulik, F. Rademakers, and J. D'hooge Echocardiographic assessment of left ventricular untwist rate: comparison of tissue Doppler and speckle tracking methodologies Eur J Echocardiogr, July 1, 2009; 10(5): 683 - 690. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. van Dalen, O. I.I. Soliman, W. B. Vletter, F. Kauer, H. B. van der Zwaan, F. J. ten Cate, and M. L. Geleijnse Feasibility and reproducibility of left ventricular rotation parameters measured by speckle tracking echocardiography Eur J Echocardiogr, July 1, 2009; 10(5): 669 - 676. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Helle-Valle, E. W. Remme, E. Lyseggen, E. Pettersen, T. Vartdal, A. Opdahl, H.-J. Smith, N. F. Osman, H. Ihlen, T. Edvardsen, et al. Clinical assessment of left ventricular rotation and strain: a novel approach for quantification of function in infarcted myocardium and its border zones Am J Physiol Heart Circ Physiol, July 1, 2009; 297(1): H257 - H267. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. T. Tan, F. Wenzelburger, E. Lee, G. Heatlie, F. Leyva, K. Patel, M. Frenneaux, and J. E. Sanderson The pathophysiology of heart failure with normal ejection fraction exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. J. Am. Coll. Cardiol., June 30, 2009; 54(1): 36 - 46. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. T. Burns, A. La Gerche, D. L. Prior, and A. I. MacIsaac Left Ventricular Untwisting Is an Important Determinant of Early Diastolic Function J. Am. Coll. Cardiol. Img., June 1, 2009; 2(6): 709 - 716. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Opdahl, E. W. Remme, T. Helle-Valle, E. Lyseggen, T. Vartdal, E. Pettersen, T. Edvardsen, and O. A. Smiseth Determinants of Left Ventricular Early-Diastolic Lengthening Velocity: Independent Contributions From Left Ventricular Relaxation, Restoring Forces, and Lengthening Load Circulation, May 19, 2009; 119(19): 2578 - 2586. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. K. Russel, M. J.W. Gotte, J. G. Bronzwaer, P. Knaapen, W. J. Paulus, and A. C. van Rossum Left ventricular torsion an expanding role in the analysis of myocardial dysfunction. J. Am. Coll. Cardiol. Img., May 1, 2009; 2(5): 648 - 655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Delgado, L. F. Tops, S. A. Trines, K. Zeppenfeld, N. Ajmone Marsan, M. Bertini, E. R. Holman, M. J. Schalij, and J. J. Bax Acute Effects of Right Ventricular Apical Pacing on Left Ventricular Synchrony and Mechanics Circ Arrhythm Electrophysiol, April 1, 2009; 2(2): 135 - 145. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B M van Dalen, F Kauer, O I I Soliman, W B Vletter, M Michels, F J t. Cate, and M L Geleijnse Influence of the pattern of hypertrophy on left ventricular twist in hypertrophic cardiomyopathy Heart, April 1, 2009; 95(8): 657 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Wang and S. F. Nagueh Current Perspectives on Cardiac Function in Patients With Diastolic Heart Failure Circulation, March 3, 2009; 119(8): 1146 - 1157. [Full Text] [PDF]
|
|
|
|
|
|
C. Goffinet, F. Chenot, A. Robert, A.-C. Pouleur, J.-B. l. P. de Waroux, D. Vancrayenest, O. Gerard, A. Pasquet, B. L. Gerber, and J.-L. Vanoverschelde Assessment of subendocardial vs. subepicardial left ventricular rotation and twist using two-dimensional speckle tracking echocardiography: comparison with tagged cardiac magnetic resonance Eur. Heart J., March 1, 2009; 30(5): 608 - 617. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. B. Ennis, T. C. Nguyen, A. Itoh, W. Bothe, D. H. Liang, N. B. Ingels, and D. C. Miller Reduced Systolic Torsion in Chronic "Pure" Mitral Regurgitation Circ Cardiovasc Imaging, March 1, 2009; 2(2): 85 - 92. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W.-J. Kim, B. H. Lee, Y. J. Kim, J. H. Kang, Y. J. Jung, J.-M. Song, D.-H. Kang, and J.-K. Song Apical Rotation Assessed by Speckle-Tracking Echocardiography as an Index of Global Left Ventricular Contractility Circ Cardiovasc Imaging, March 1, 2009; 2(2): 123 - 131. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. H. Bijnens, M. Cikes, P. Claus, and G. R. Sutherland Velocity and deformation imaging for the assessment of myocardial dysfunction Eur J Echocardiogr, March 1, 2009; 10(2): 216 - 226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. F. Nagueh, C. P. Appleton, T. C. Gillebert, P. N. Marino, J. K. Oh, O. A. Smiseth, A. D. Waggoner, F. A. Flachskampf, P. A. Pellikka, and A. Evangelisa Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography Eur J Echocardiogr, March 1, 2009; 10(2): 165 - 193. [Full Text] [PDF]
|
|
|
|
|
|
T. P. Abraham and H.-Y. Liang Stress echocardiography diastole to the rescue. J. Am. Coll. Cardiol., February 24, 2009; 53(8): 706 - 708. [Full Text] [PDF]
|
|
|
|
 |
|
 B. T. Esch and D. E. R. Warburton Left ventricular torsion and recoil: implications for exercise performance and cardiovascular disease J Appl Physiol, February 1, 2009; 106(2): 362 - 369. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Saito, H Okayama, K Nishimura, A Ogimoto, T Ohtsuka, K Inoue, G Hiasa, T Sumimoto, J Funada, Y Shigematsu, et al. Determinants of left ventricular untwisting behaviour in patients with dilated cardiomyopathy: analysis by two-dimensional speckle tracking Heart, February 1, 2009; 95(4): 290 - 296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Gustafsson, P. Lindqvist, S. Morner, and A. Waldenstrom Assessment of regional rotation patterns improves the understanding of the systolic and diastolic left ventricular function: an echocardiographic speckle-tracking study in healthy individuals Eur J Echocardiogr, January 1, 2009; 10(1): 56 - 61. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Nishikage, H. Nakai, V. Mor-Avi, R. M. Lang, I. S. Salgo, S. H. Settlemier, S. Husson, and M. Takeuchi Quantitative assessment of left ventricular volume and ejection fraction using two-dimensional speckle tracking echocardiography Eur J Echocardiogr, January 1, 2009; 10(1): 82 - 88. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. S. Halvorsen, A. Espinoza, L. A. Fleischer, O. J. Elle, L. Hoff, R. Lundblad, H. Skulstad, T. Edvardsen, H. Ihlen, and E. Fosse Feasibility of a three-axis epicardial accelerometer in detecting myocardial ischemia in cardiac surgical patients. J. Thorac. Cardiovasc. Surg., December 1, 2008; 136(6): 1496 - 1502. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Marcucci, R. Lauer, and A. Mahajan New Echocardiographic Techniques for Evaluating Left Ventricular Myocardial Function Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2008; 12(4): 228 - 247. [Abstract] [PDF]
|
|
|
|
|
|
L. C. Afonso, J. Bernal, J. J. Bax, and T. P. Abraham Echocardiography in hypertrophic cardiomyopathy: the role of conventional and emerging technologies. J. Am. Coll. Cardiol. Img., November 1, 2008; 1(6): 787 - 800. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Gjesdal, T. Helle-Valle, E. Hopp, K. Lunde, T. Vartdal, S. Aakhus, H.-J. Smith, H. Ihlen, and T. Edvardsen Noninvasive Separation of Large, Medium, and Small Myocardial Infarcts in Survivors of Reperfused ST-Elevation Myocardial Infarction: A Comprehensive Tissue Doppler and Speckle-Tracking Echocardiography Study Circ Cardiovasc Imaging, November 1, 2008; 1(3): 189 - 196. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. van Dalen, K. Caliskan, O. I.I. Soliman, A. Nemes, W. B. Vletter, F. J. ten Cate, and M. L. Geleijnse Left ventricular solid body rotation in non-compaction cardiomyopathy: A potential new objective and quantitative functional diagnostic criterion? Eur J Heart Fail, November 1, 2008; 10(11): 1088 - 1093. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Perry, C. G. De Pasquale, D. P. Chew, and M. X. Joseph Assessment of early diastolic left ventricular function by two-dimensional echocardiographic speckle tracking Eur J Echocardiogr, November 1, 2008; 9(6): 791 - 795. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q Zhang, J W-H Fung, G W K Yip, J Y-S Chan, A P-W Lee, Y-Y Lam, L-W Wu, E B Wu, and C-M Yu Improvement of left ventricular myocardial short-axis, but not long-axis function or torsion after cardiac resynchronisation therapy: an assessment by two-dimensional speckle tracking Heart, November 1, 2008; 94(11): 1464 - 1471. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Nottin, G. Doucende, I. Schuster-Beck, M. Dauzat, and P. Obert Alteration in left ventricular normal and shear strains evaluated by 2D-strain echocardiography in the athlete's heart J. Physiol., October 1, 2008; 586(19): 4721 - 4733. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. van Dalen, O. I. I. Soliman, W. B. Vletter, F. J. ten Cate, and M. L. Geleijnse Age-related changes in the biomechanics of left ventricular twist measured by speckle tracking echocardiography Am J Physiol Heart Circ Physiol, October 1, 2008; 295(4): H1705 - H1711. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A T Burns, I G McDonald, J D Thomas, A MacIsaac, and D Prior Doin' the twist: new tools for an old concept of myocardial function Heart, August 1, 2008; 94(8): 978 - 983. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N R Van de Veire, J De Sutter, J J Bax, and J R T C Roelandt Technological advances in tissue Doppler imaging echocardiography Heart, August 1, 2008; 94(8): 1065 - 1074. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Aase, H. Torp, and A. Stoylen Aortic valve closure: relation to tissue velocities by Doppler and speckle tracking in normal subjects Eur J Echocardiogr, July 1, 2008; 9(4): 555 - 559. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Wang, D. S. Khoury, Y. Yue, G. Torre-Amione, and S. F. Nagueh Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failure Eur. Heart J., May 2, 2008; 29(10): 1283 - 1289. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. C. Gillebert and N. R. Van de Veire About left ventricular torsion, sex differences, shear strain, and diastolic heart failure Eur. Heart J., May 2, 2008; 29(10): 1215 - 1217. [Full Text] [PDF]
|
|
|
|
|
|
P. P. Sengupta, A. J. Tajik, K. Chandrasekaran, and B. K. Khandheria Twist mechanics of the left ventricle principles and application. J. Am. Coll. Cardiol. Img., May 1, 2008; 1(3): 366 - 376. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A N Borg, J L Harrison, R A Argyle, and S G Ray Left ventricular torsion in primary chronic mitral regurgitation Heart, May 1, 2008; 94(5): 597 - 603. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Becker, A. Lenzen, C. Ocklenburg, K. Stempel, H. Kuhl, M. Neizel, M. Katoh, R. Kramann, J. Wildberger, M. Kelm, et al. Myocardial Deformation Imaging Based on Ultrasonic Pixel Tracking to Identify Reversible Myocardial Dysfunction J. Am. Coll. Cardiol., April 15, 2008; 51(15): 1473 - 1481. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Dorfman, B. D. Rosen, M. A. Perhonen, T. Tillery, R. McColl, R. M. Peshock, and B. D. Levine Diastolic suction is impaired by bed rest: MRI tagging studies of diastolic untwisting J Appl Physiol, April 1, 2008; 104(4): 1037 - 1044. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z B Popovic, R A Grimm, A Ahmad, D Agler, M Favia, G Dan, P Lim, F Casas, N L Greenberg, and J D Thomas Longitudinal rotation: an unrecognised motion pattern in patients with dilated cardiomyopathy Heart, March 1, 2008; 94(3): e11 - e11. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lindqvist, A. Calcutteea, and M. Henein Echocardiography in the assessment of right heart function Eur J Echocardiogr, March 1, 2008; 9(2): 225 - 234. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Abraham and A. C. Pinheiro Speckle-Derived Strain: A Better Tool for Quantification of Stress Echocardiography? J. Am. Coll. Cardiol., January 15, 2008; 51(2): 158 - 160. [Full Text] [PDF]
|
|
|
|
|
|
P. P. Sengupta, V. K. Krishnamoorthy, W. P. Abhayaratna, J. Korinek, M. Belohlavek, T. M. Sundt III, K. Chandrasekaran, F. Mookadam, J. B. Seward, A. J. Tajik, et al. Disparate patterns of left ventricular mechanics differentiate constrictive pericarditis from restrictive cardiomyopathy. J. Am. Coll. Cardiol. Img., January 1, 2008; 1(1): 29 - 38. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Penny, J. P. Mynard, and J. J. Smolich Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep Am J Physiol Heart Circ Physiol, January 1, 2008; 294(1): H481 - H489. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Rakowski and S. Carasso Quantifying Diastolic Function in Hypertrophic Cardiomyopathy: The Ongoing Search for the Holy Grail Circulation, December 4, 2007; 116(23): 2662 - 2665. [Full Text] [PDF]
|
|
|
|
|
|
J. Wang, D. S. Khoury, Y. Yue, G. Torre-Amione, and S. F. Nagueh Left Ventricular Untwisting Rate by Speckle Tracking Echocardiography Circulation, November 27, 2007; 116(22): 2580 - 2586. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Takeuchi, W. B. Borden, H. Nakai, T. Nishikage, M. Kokumai, T. Nagakura, S. Otani, and R. M Lang Reduced and delayed untwisting of the left ventricle in patients with hypertension and left ventricular hypertrophy: a study using two-dimensional speckle tracking imaging Eur. Heart J., November 2, 2007; 28(22): 2756 - 2762. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. N. Kirkpatrick, M. A. Vannan, J. Narula, and R. M. Lang Echocardiography in Heart Failure: Applications, Utility, and New Horizons J. Am. Coll. Cardiol., July 31, 2007; 50(5): 381 - 396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Pettersen, T. Helle-Valle, T. Edvardsen, H. Lindberg, H.-J. Smith, B. Smevik, O. A. Smiseth, and K. Andersen Contraction Pattern of the Systemic Right Ventricle: Shift From Longitudinal to Circumferential Shortening and Absent Global Ventricular Torsion J. Am. Coll. Cardiol., June 26, 2007; 49(25): 2450 - 2456. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. B. Popovic, C. Benejam, J. Bian, N. Mal, J. Drinko, K. Lee, F. Forudi, R. Reeg, N. L. Greenberg, J. D. Thomas, et al. Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction Am J Physiol Heart Circ Physiol, June 1, 2007; 292(6): H2809 - H2816. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Weyman The Year in Echocardiography J. Am. Coll. Cardiol., March 20, 2007; 49(11): 1212 - 1219. [Full Text] [PDF]
|
|
|
|
|
|
J. D. Thomas and Z. B. Popovic Assessment of Left Ventricular Function by Cardiac Ultrasound J. Am. Coll. Cardiol., November 21, 2006; 48(10): 2012 - 2025. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Foster and K. E. Lease New Untwist on Diastole: What Goes Around Comes Back Circulation, May 30, 2006; 113(21): 2477 - 2479. [Full Text] [PDF]
|
|