Published online before print September 20, 2004, doi: 10.1161/01.CIR.0000142670.65971.5F
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Circulation. 2004;110:1814-1818.)
© 2004 American Heart Association, Inc.
Imaging |
Fast Measurement of Left Ventricular Mass With Real-Time Three-Dimensional Echocardiography
Comparison With Magnetic Resonance Imaging
From the Noninvasive Cardiac Imaging Laboratory, University of Chicago, Chicago, Ill (V.M.-A., L.S., L.W., P.M., E.G.C., R.K., R.M.L.); Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy (E.G.C.); and Philips Medical Systems, Andover, Mass (I.S.S.).
Correspondence to Victor Mor-Avi, PhD, University of Chicago MC5084, 5841 S. Maryland Ave, Chicago Illinois 60637. E-mail vmoravi{at}medicine.bsd.uchicago.edu
Received February 3, 2004; de novo received March 17, 2004; revision received May 24, 2004; accepted May 26, 2004.
Background— Left ventricular (LV) mass is an important predictor of morbidity and mortality, especially in patients with systemic hypertension. However, the accuracy of 2D echocardiographic LV mass measurements is limited because acquiring anatomically correct apical views is often difficult. We tested the hypothesis that LV mass could be measured more accurately from real-time 3D (RT3D) data sets, which allow offline selection of nonforeshortened apical views, by comparing 2D and RT3D measurements against cardiac MR (CMR) measurements.
Methods and Results— Echocardiographic imaging was performed (Philips 7500) in 21 patients referred for CMR imaging (1.5 T, GE). Apical 2- and 4-chamber views and RT3D data sets were acquired and analyzed by 2 independent observers. The RT3D data sets were used to select nonforeshortened apical 2- and 4-chamber views (3DQ-QLAB, Philips). In both 2D and RT3D images, LV long axis was measured; endocardial and epicardial boundaries were traced, and mass was calculated by use of the biplane method of disks. CMR LV mass values were obtained through standard techniques (MASS Analysis, GE). The RT3D data resulted in significantly larger LV long-axis dimensions and measurements of LV mass that correlated with CMR better (r=0.90) than 2D (r=0.79). The 2D technique underestimated LV mass (bias, 39%), whereas RT3D measurements showed only minimal bias (3%). The 95% limits of agreement were significantly wider for 2D (52%) than RT3D (28%). Additionally, the RT3D technique reduced the interobserver variability (37% to 7%) and intraobserver variability (19% to 8%).
Conclusions— RT3D imaging provides the basis for accurate and reliable measurement of LV mass.
Key Words: imaging • echocardiography • hypertrophy, left ventricular
This article has been cited by other articles:
 |
|
 |
|
  N. A. Marsan, L. F Tops, P. Nihoyannopoulos, E. R Holman, and J. J Bax Real-time three dimensional echocardiography: current and future clinical applications Heart, November 15, 2009; 95(22): 1881 - 1890. [Full Text] [PDF]
|
|
|
|
 |
|
 H.-J. Nesser, V. Mor-Avi, W. Gorissen, L. Weinert, R. Steringer-Mascherbauer, J. Niel, L. Sugeng, and R. M. Lang Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: comparison with MRI Eur. Heart J., July 1, 2009; 30(13): 1565 - 1573. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Mor-Avi, L. Sugeng, and R. M. Lang Real-Time 3-Dimensional Echocardiography: An Integral Component of the Routine Echocardiographic Examination in Adult Patients? Circulation, January 20, 2009; 119(2): 314 - 329. [Full Text] [PDF]
|
|
|
|
|
|
J Pemberton, M Jerosch-Herold, X Li, L Hui, M Silberbach, W Woodward, K Thiele, A Kenny, and D J Sahn Accuracy of real-time, three-dimensional Doppler echocardiography for stroke volume estimation compared with phase-encoded MRI: an in vivo study Heart, September 1, 2008; 94(9): 1212 - 1213. [Full Text] [PDF]
|
|
|
|
|
|
A-C Pouleur, J-B le Polain de Waroux, A Pasquet, B L Gerber, O Gerard, P Allain, and J-L J Vanoverschelde Assessment of left ventricular mass and volumes by three-dimensional echocardiography in patients with or without wall motion abnormalities: comparison against cine magnetic resonance imaging Heart, August 1, 2008; 94(8): 1050 - 1057. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Mor-Avi, C. Jenkins, H. P. Kuhl, H.-J. Nesser, T. Marwick, A. Franke, C. Ebner, B. H. Freed, R. Steringer-Mascherbauer, H. Pollard, et al. Real-time 3-dimensional echocardiographic quantification of left ventricular volumes multicenter study for validation with magnetic resonance imaging and investigation of sources of error. J. Am. Coll. Cardiol. Img., July 1, 2008; 1(4): 413 - 423. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.-C. Yap, R.-J. M. van Geuns, A. Nemes, F. J. Meijboom, J. S. McGhie, M. L. Geleijnse, M. L. Simoons, and J. W. Roos-Hesselink Rapid and accurate measurement of LV mass by biplane real-time 3D echocardiography in patients with concentric LV hypertrophy: comparison to CMR Eur J Echocardiogr, March 1, 2008; 9(2): 255 - 260. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Agabiti-Rosei, M. L. Muiesan, and M. Salvetti Review: New approaches to the assessment of left ventricular hypertrophy Therapeutic Advances in Cardiovascular Disease, December 1, 2007; 1(2): 119 - 128. [Abstract] [PDF]
|
|
|
|
 |
|
 J. N. Kirkpatrick, M. A. Vannan, J. Narula, and R. M. Lang Echocardiography in Heart Failure: Applications, Utility, and New Horizons J. Am. Coll. Cardiol., July 31, 2007; 50(5): 381 - 396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A H Gershlick, M de Belder, J Chambers, D Hackett, R Keal, A Kelion, S Neubauer, D J Pennell, M Rothman, M Signy, et al. Role of non-invasive imaging in the management of coronary artery disease: an assessment of likely change over the next 10 years. A report from the British Cardiovascular Society Working Group Heart, April 1, 2007; 93(4): 423 - 431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Thomas and Z. B. Popovic Assessment of Left Ventricular Function by Cardiac Ultrasound J. Am. Coll. Cardiol., November 21, 2006; 48(10): 2012 - 2025. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Lang, V. Mor-Avi, L. Sugeng, P. S. Nieman, and D. J. Sahn Three-Dimensional Echocardiography: The Benefits of the Additional Dimension J. Am. Coll. Cardiol., November 21, 2006; 48(10): 2053 - 2069. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. C. Houck, J. E. Cooke, and E. A. Gill Live 3D Echocardiography: A Replacement for Traditional 2D Echocardiography? Am. J. Roentgenol., October 1, 2006; 187(4): 1092 - 1106. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. L. Chuang and W. J. Manning Pitfalls in comparison of left ventricular mass measurements by echocardiography and cardiovascular magnetic resonance imaging Nephrol. Dial. Transplant., September 1, 2006; 21(9): 2668 - 2668. [Full Text] [PDF]
|
|
|
|
|
|
L. Sugeng, V. Mor-Avi, L. Weinert, J. Niel, C. Ebner, R. Steringer-Mascherbauer, F. Schmidt, C. Galuschky, G. Schummers, R. M. Lang, et al. Quantitative Assessment of Left Ventricular Size and Function: Side-by-Side Comparison of Real-Time Three-Dimensional Echocardiography and Computed Tomography With Magnetic Resonance Reference Circulation, August 15, 2006; 114(7): 654 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. G. Caiani, L. Sugeng, L. Weinert, A. Capderou, R. M. Lang, and P. Vaida Objective evaluation of changes in left ventricular and atrial volumes during parabolic flight using real-time three-dimensional echocardiography J Appl Physiol, August 1, 2006; 101(2): 460 - 468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Fukuda, G. Saracino, Y. Matsumura, M. Daimon, H. Tran, N. L. Greenberg, T. Hozumi, J. Yoshikawa, J. D. Thomas, and T. Shiota Three-Dimensional Geometry of the Tricuspid Annulus in Healthy Subjects and in Patients With Functional Tricuspid Regurgitation: A Real-Time, 3-Dimensional Echocardiographic Study Circulation, July 4, 2006; 114(1_suppl): I-492 - I-498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Lang, M. Bierig, R. B. Devereux, F. A. Flachskampf, E. Foster, P. A. Pellikka, M. H. Picard, M. J. Roman, J. Seward, J. Shanewise, et al. Recommendations for chamber quantification Eur J Echocardiogr, March 1, 2006; 7(2): 79 - 108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. D. Jacobs, I. S. Salgo, S. Goonewardena, L. Weinert, P. Coon, D. Bardo, O. Gerard, P. Allain, J. L. Zamorano, L. P. de Isla, et al. Rapid online quantification of left ventricular volume from real-time three-dimensional echocardiographic data Eur. Heart J., February 2, 2006; 27(4): 460 - 468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E G Caiani, C Corsi, L Sugeng, P MacEneaney, L Weinert, V Mor-Avi, and R M Lang Improved quantification of left ventricular mass based on endocardial and epicardial surface detection with real time three dimensional echocardiography Heart, February 1, 2006; 92(2): 213 - 219. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Tsutsui, E. E. Martinez, C. E. Rochitte, J. F. Ramires, and W. Mathias Jr. Noninvasive evaluation of left circumflex coronary aneurysm by real-time three-dimensional echocardiography Eur J Echocardiogr, January 1, 2006; 7(1): 75 - 78. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J Monaghan Role of real time 3D echocardiography in evaluating the left ventricle Heart, January 1, 2006; 92(1): 131 - 136. [Full Text] [PDF]
|
|
|
|
 |
|
 J. Chambers, K. Fox, and A. Fraser Recent advances in non-invasive cardiology: Article does not mention echocardiography BMJ, March 26, 2005; 330(7493): 731 - 731. [Full Text]
|
|