Circulation. 2004;109:1244-1249
Published online before print February 23, 2004, doi: 10.1161/01.CIR.0000118474.71662.E3
Published online before print February 23, 2004, doi: 10.1161/01.CIR.0000118474.71662.E3
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(Circulation. 2004;109:1244-1249.)
© 2004 American Heart Association, Inc.
Clinical Investigation and Reports |
Randomized Study to Evaluate Sirolimus-Eluting Stents Implanted at Coronary Bifurcation Lesions
From EMO Centro Cuore Columbus, Milan, Italy (A.C., C.D.M.); Lenox Hill Hospital, New York, NY (J.W.M., M.B.L.); Institut Cardiovasculaire Paris Sud, Massy, France (M.C.M., Y.L.); University Heart Center Erlangen, Germany (J.L.); Mayo Clinic, Rochester, Minn (D.R.H.); Milan Cardiovascular Research, Milan, Italy (V.S.); and Cordis Corp, Waterloo, Brussels (B.D.).
Correspondence to Antonio Colombo, MD, Centro Cuore Columbus, Via M. Buonarroti 48, 20145 Milan, Italy. E-mail info{at}emocolumbus.it
Received July 11, 2003; de novo received September 24, 2003; revision received December 8, 2003; accepted December 10, 2003.
Background— A sirolimus-eluting stent (Cypher, Cordis Corp) has been reported to markedly decrease restenosis in selected lesions; higher-risk lesions, including coronary bifurcations, have not been studied.
Methods and Results— This prospective study evaluated the safety and efficacy of sirolimus-eluting stents for treatment of coronary bifurcation lesions. Patients were randomly assigned to either stenting of both branches (group A) or stenting of the main branch with provisional stenting of the side branch (SB) (group B). Eighty-five patients (86 lesions) were enrolled. There was 1 case of unsuccessful delivery of any device at the bifurcation site. Given the high crossover, more lesions were treated with 2 stents (n=63) than with stent/balloon (n=22). Clinical follow-up at 6 months was completed in all patients and angiographic follow-up in 53 patients in group A (85.5%) and 21 in group B (95.4%). One patient died suddenly 4.5 months after the procedure. There were 3 cases of stent thrombosis (3.5%). The total restenosis rate at 6 months was 25.7%, and it was not significantly different between the double-stenting (28.0%) and the provisional SB-stenting (18.7%) groups. Fourteen of the restenosis cases occurred at the ostium of the SB and were focal. Target lesion revascularization was performed in 7 cases; target vessel failure occurred in 15 cases (17.6%).
Conclusions— These results are an improvement compared with historical controls using bare metal stents. Restenosis at the SB remains a problem. At this time, no statement can be made regarding the most appropriate technique to use when treating bifurcations with the Cypher stent.
Key Words: stents • drugs • restenosis
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|
|
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|
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|
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|
|
|
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|
|
|
|
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|
|
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|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
P. Urban, A. H. Gershlick, G. Guagliumi, P. Guyon, C. Lotan, J. Schofer, A. Seth, J. E. Sousa, W. Wijns, C. Berge, et al. Safety of Coronary Sirolimus-Eluting Stents in Daily Clinical Practice: One-Year Follow-Up of the e-Cypher Registry Circulation, March 21, 2006; 113(11): 1434 - 1441. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L Ge, I Iakovou, J Cosgrave, P Agostoni, F Airoldi, G M Sangiorgi, I Michev, A Chieffo, M Montorfano, M Carlino, et al. Treatment of bifurcation lesions with two stents: one year angiographic and clinical follow up of crush versus T stenting Heart, March 1, 2006; 92(3): 371 - 376. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Price, E. Cristea, N. Sawhney, J. A. Kao, J. W. Moses, M. B. Leon, R. A. Costa, A. J. Lansky, and P. S. Teirstein Serial Angiographic Follow-Up of Sirolimus-Eluting Stents for Unprotected Left Main Coronary Artery Revascularization J. Am. Coll. Cardiol., February 21, 2006; 47(4): 871 - 877. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. S. Baim, L. Mauri, and D. C. Cutlip Drug-Eluting Stenting for Unprotected Left Main Coronary Artery Disease: Are We Ready to Replace Bypass Surgery? J. Am. Coll. Cardiol., February 21, 2006; 47(4): 878 - 881. [Full Text] [PDF]
|
|
|
|
 |
|
 P. W. Serruys, M. J.B. Kutryk, and A. T.L. Ong Coronary-Artery Stents N. Engl. J. Med., February 2, 2006; 354(5): 483 - 495. [Full Text] [PDF]
|
|
|
|
|
|
H. Kelbaek, L. Thuesen, S. Helqvist, L. Klovgaard, E. Jorgensen, S. Aljabbari, K. Saunamaki, L. R. Krusell, G. V.H. Jensen, H. E. Botker, et al. The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) Trial J. Am. Coll. Cardiol., January 17, 2006; 47(2): 449 - 455. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kelbaek, L. Thuesen, S. Helqvist, L. Klovgaard, E. Jorgensen, S. Aljabbari, K. Saunamaki, L. R. Krusell, G. V.H. Jensen, H. E. Botker, et al. The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) Trial J. Am. Coll. Cardiol., December 13, 2005; (2005) j.jacc.2005.10.045v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Alvarez Jr and N. K. Kapur Drug Eluting Stent Technology: A Paradigm Shift in the Treatment and Prevention of Restenosis Journal of Pharmacy Practice, December 1, 2005; 18(6): 461 - 478. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Pislaru and R. D. Simari The Translation of Transcription Circ. Res., November 25, 2005; 97(11): 1083 - 1084. [Full Text] [PDF]
|
|
|
|
|
|
I. Iakovou, L. Ge, and A. Colombo Contemporary Stent Treatment of Coronary Bifurcations J. Am. Coll. Cardiol., October 18, 2005; 46(8): 1446 - 1455. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Davidavicius, F. Van Praet, S. Mansour, F. Casselman, J. Bartunek, I. Degrieck, F. Wellens, R. De Geest, H. Vanermen, W. Wijns, et al. Hybrid Revascularization Strategy: A Pilot Study on the Association of Robotically Enhanced Minimally Invasive Direct Coronary Artery Bypass Surgery and Fractional Flow Reserve-Guided Percutaneous Coronary Intervention Circulation, August 30, 2005; 112(9_suppl): I-317 - I-322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Lefevre, J. Ormiston, G. Guagliumi, H.-P. Schultheiss, L. Quilliet, B. Reimers, P. Brunel, W. Wijns, H.J. Buettner, F. Hartmann, et al. The FRONTIER Stent Registry: Safety and Feasibility of a Novel Dedicated Stent for the Treatment of Bifurcation Coronary Artery Lesions J. Am. Coll. Cardiol., August 16, 2005; 46(4): 592 - 598. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. A. Costa, G. S. Mintz, S. G. Carlier, A. J. Lansky, I. Moussa, K. Fujii, H. Takebayashi, T. Yasuda, J. R. Costa Jr, Y. Tsuchiya, et al. Bifurcation Coronary Lesions Treated With the "Crush" Technique: An Intravascular Ultrasound Analysis J. Am. Coll. Cardiol., August 16, 2005; 46(4): 599 - 605. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Garot, T. Lefevre, M. Savage, Y. Louvard, W. R. Bamlet, J. T. Willerson, M.-C. Morice, and D. R. Holmes Jr Nine-Month Outcome of Patients Treated by Percutaneous Coronary Interventions for Bifurcation Lesions in the Recent Era: A Report From the Prevention of Restenosis With Tranilast and its Outcomes (PRESTO) Trial J. Am. Coll. Cardiol., August 16, 2005; 46(4): 606 - 612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Ge, F. Airoldi, I. Iakovou, J. Cosgrave, I. Michev, G. M. Sangiorgi, M. Montorfano, A. Chieffo, M. Carlino, N. Corvaja, et al. Clinical and Angiographic Outcome After Implantation of Drug-Eluting Stents in Bifurcation Lesions With the Crush Stent Technique: Importance of Final Kissing Balloon Post-Dilation J. Am. Coll. Cardiol., August 16, 2005; 46(4): 613 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. O. Williams and J. D. Abbott Bifurcation Intervention: Is it Crush Time Yet? J. Am. Coll. Cardiol., August 16, 2005; 46(4): 621 - 624. [Full Text] [PDF]
|
|
|
|
|
|
B.-K. Koo, H.-J. Kang, T.-J. Youn, I.-H. Chae, D.-J. Choi, H.-S. Kim, D.-W. Sohn, B.-H. Oh, M.-M. Lee, Y.-B. Park, et al. Physiologic Assessment of Jailed Side Branch Lesions Using Fractional Flow Reserve J. Am. Coll. Cardiol., August 16, 2005; 46(4): 633 - 637. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Hausleiter, A. Kastrati, R. Wessely, A. Dibra, J. Mehilli, T. Schratzenstaller, I. Graf, M. Renke-Gluszko, B. Behnisch, J. Dirschinger, et al. Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating Eur. Heart J., August 1, 2005; 26(15): 1475 - 1481. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M R Thomas Brachytherapy: here today, gone tomorrow? Heart, June 1, 2005; 91(suppl_3): iii32 - iii34. [Full Text] [PDF]
|
|
|
|
|
|
W. W. O'Neill, S. R. Dixon, and C. L. Grines The year in interventional cardiology J. Am. Coll. Cardiol., April 5, 2005; 45(7): 1117 - 1134. [Full Text] [PDF]
|
|
|
|
 |
|
 R. Wessely, J. Hausleiter, C. Michaelis, B. Jaschke, M. Vogeser, S. Milz, B. Behnisch, T. Schratzenstaller, M. Renke-Gluszko, M. Stover, et al. Inhibition of Neointima Formation by a Novel Drug-Eluting Stent System That Allows for Dose-Adjustable, Multiple, and On-Site Stent Coating Arterioscler. Thromb. Vasc. Biol., April 1, 2005; 25(4): 748 - 753. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Valgimigli, C. A.G. van Mieghem, A. T.L. Ong, J. Aoki, G. A. R. Granillo, E. P. McFadden, A. P. Kappetein, P. J. de Feyter, P. C. Smits, E. Regar, et al. Short- and Long-Term Clinical Outcome After Drug-Eluting Stent Implantation for the Percutaneous Treatment of Left Main Coronary Artery Disease: Insights From the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital Registries (RESEARCH and T-SEARCH) Circulation, March 22, 2005; 111(11): 1383 - 1389. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T.L. Ong, A. Hoye, J. Aoki, C. A.G. van Mieghem, G. A. Rodriguez Granillo, K. Sonnenschein, E. Regar, E. P. McFadden, G. Sianos, W. J. van der Giessen, et al. Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation J. Am. Coll. Cardiol., March 15, 2005; 45(6): 947 - 953. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-J. Park, Y.-H. Kim, B.-K. Lee, S.-W. Lee, C. W. Lee, M.-K. Hong, J.-J. Kim, G. S. Mintz, and S.-W. Park Sirolimus-eluting stent implantation for unprotected left main coronary artery stenosis: Comparison with bare metal stent implantation J. Am. Coll. Cardiol., February 1, 2005; 45(3): 351 - 356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
A. Kastrati, J. Mehilli, N. von Beckerath, A. Dibra, J. Hausleiter, J. Pache, H. Schuhlen, C. Schmitt, J. Dirschinger, A. Schomig, et al. Sirolimus-Eluting Stent or Paclitaxel-Eluting Stent vs Balloon Angioplasty for Prevention of Recurrences in Patients With Coronary In-Stent Restenosis: A Randomized Controlled Trial JAMA, January 12, 2005; 293(2): 165 - 171. [Abstract] [Full Text] [PDF]
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A. Colombo and I. Iakovou Drug-eluting stents: the new gold standard for percutaneous coronary revascularisation Eur. Heart J., June 1, 2004; 25(11): 895 - 897. [Full Text] [PDF]
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P. S. Teirstein A Chicken in Every Pot and a Drug-Eluting Stent in Every Lesion Circulation, April 27, 2004; 109(16): 1906 - 1910. [Full Text] [PDF]
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