| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Circulation. 2002;105:1099.)
© 2002 American Heart Association, Inc.
Clinical Investigation and Reports |
From the Pediatric Heart Center, Justus-Liebig University Giessen, Germany.
Correspondence to Dietmar Schranz, MD, Pediatric Heart Center, Justus-Liebig University, Feulgenstraße 12, 35385 Giessen, Germany. E-mail Dietmar.Schranz{at}paediat.med.uni-giessen.de
Background Outcome of patients with hypoplastic left heart (HLH) is mainly influenced by the successful first-step palliation according to the Norwood procedure. An alternative approach is heart transplantation (HTX). The feasibility of ductal stenting in newborns with duct-dependent systemic blood flow and bilateral pulmonary artery banding has been reported. But it remains to be elucidated whether this approach allows a new strategy for patients with HLH.
Methods and Results In patients with various forms of HLH (n=11) and prostaglandin E-1 administration, ductal stenting was performed with balloon expandable Jo stents or Saxx stents. Bilateral pulmonary artery banding was surgically accomplished 1 to 3 days after the transcatheter procedure. Unrestricted blood flow through the interatrial septum was secured by balloon dilatation atrial septotomy, as required. Interventional procedures were performed with no mortality. Stent and ductal patency were achieved for up to 331 days. Two patients underwent HTX, and 8 patients had a palliative 1-stage procedure with reconstruction of the aortic arch and bidirectional cavopulmonary connection at the age of 3.5 to 6 months. There were 2 deaths. One patient with preoperative right heart failure died after the reconstructive surgery, and 1 patient died 4 months after ductal stenting and bilateral banding awaiting HTX.
Conclusions The present study is the first clinical trial showing that stenting the duct followed by bilateral pulmonary artery banding in newborns with HLH allows the combination of neoaortic reconstruction, which is part of first-stage palliation of HLH, with the establishment of a bidirectional cavopulmonary connection. Additionally, it allows the chance for HTX after extended waiting periods.
Key Words: ductus arteriosus, patent stents pediatrics heart defects, congenital
This article has been cited by other articles:
![]() |
U. E Salzer-Muhar Life after the Norwood procedure Heart, August 1, 2009; 95(15): 1211 - 1213. [Full Text] [PDF] |
||||
![]() |
A. M. Fabricius, T. J. Jones, J. Stickley, O. Stumper, A. Chikermane, T. Desai, P. Miller, R. Dhillon, J. V. de Giovanni, J. G. Wright, et al. Surgical management of hypoplastic left heart syndrome at the Birmingham Children's Hospital MMCTS, July 24, 2009; 2009(0724): 2378. [Abstract] [Full Text] [PDF] |
||||
![]() |
Q. Chen and A. J. Parry The current role of hybrid procedures in the stage 1 palliation of patients with hypoplastic left heart syndrome Eur. J. Cardiothorac. Surg., July 1, 2009; 36(1): 77 - 83. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Honjo, L. N. Benson, H. E. Mewhort, D. Predescu, H. Holtby, G. S. Van Arsdell, and C. A. Caldarone Clinical Outcomes, Program Evolution, and Pulmonary Artery Growth in Single Ventricle Palliation Using Hybrid and Norwood Palliative Strategies. Ann. Thorac. Surg., June 1, 2009; 87(6): 1885 - 1893. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Pizarro, M. A. Bhat, C. D. Derby, and W. A. Radtke Bailout after failed biventricular management of critical aortic stenosis: another application of the hybrid approach. Ann. Thorac. Surg., May 1, 2009; 87(5): e40 - e42. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Schmitz, B. Esmailzadeh, U. Herberg, N. Lang, R. Sodian, R. Kozlik-Feldmann, A. Welz, and J. Breuer Hybrid procedures can reduce the risk of congenital cardiovascular surgery Eur. J. Cardiothorac. Surg., October 1, 2008; 34(4): 718 - 725. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Galantowicz, J. P. Cheatham, A. Phillips, C. L. Cua, T. M. Hoffman, S. L. Hill, and R. Rodeman Hybrid Approach for Hypoplastic Left Heart Syndrome: Intermediate Results After the Learning Curve Ann. Thorac. Surg., June 1, 2008; 85(6): 2063 - 2071. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Pizarro, C. D. Derby, J. M. Baffa, K. A. Murdison, and W. A. Radtke Improving the outcome of high-risk neonates with hypoplastic left heart syndrome: hybrid procedure or conventional surgical palliation? Eur. J. Cardiothorac. Surg., April 1, 2008; 33(4): 613 - 618. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Pizarro, K. A. Murdison, C. D. Derby, and W. Radtke Stage II Reconstruction After Hybrid Palliation for High-Risk Patients With a Single Ventricle Ann. Thorac. Surg., April 1, 2008; 85(4): 1382 - 1388. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. B.M. Phillips Letter by Phillips Regarding Article, "Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study" Circulation, March 25, 2008; 117(12): e295 - e295. [Full Text] [PDF] |
||||
![]() |
D. Schranz, I. Michel-Behnke, and H. Akintuerk Letter by Schranz et al Regarding Article, "Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study" Circulation, March 25, 2008; 117(12): e296 - e296. [Full Text] [PDF] |
||||
![]() |
J. Li, G. Zhang, L. Benson, H. Holtby, S. Cai, T. Humpl, G. S. Van Arsdell, A. N. Redington, and C. A. Caldarone Response to Letters Regarding Article, "Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study" Circulation, March 25, 2008; 117(12): e297 - e298. [Full Text] [PDF] |
||||
![]() |
E. J. Hickey, C. A. Caldarone, E. H. Blackstone, G. K. Lofland, T. Yeh Jr, C. Pizarro, C. I. Tchervenkov, F. Pigula, D. M. Overman, M. L. Jacobs, et al. Critical left ventricular outflow tract obstruction: The disproportionate impact of biventricular repair in borderline cases. J. Thorac. Cardiovasc. Surg., December 1, 2007; 134(6): 1429 - 1437.e7. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. A. Caldarone, O. Honjo, L. N. Benson, and G. S. Van Arsdell Modification of stage II procedure after hybrid palliation (bilateral pulmonary artery banding and ductal stenting) for hypoplastic left-sided heart syndrome: Modified arch reconstruction with retained stented ductus patch. J. Thorac. Cardiovasc. Surg., December 1, 2007; 134(6): 1588 - 1589. [Full Text] [PDF] |
||||
![]() |
C. A. Caldarone, L. Benson, H. Holtby, J. Li, A. N. Redington, and G. S. Van Arsdell Initial Experience With Hybrid Palliation for Neonates With Single-Ventricle Physiology Ann. Thorac. Surg., October 1, 2007; 84(4): 1294 - 1300. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Li, G. Zhang, L. Benson, H. Holtby, S. Cai, T. Humpl, G. S. Van Arsdell, A. N. Redington, and C. A. Caldarone Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study Circulation, September 11, 2007; 116(11_suppl): I-179 - I-187. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Alsoufi, T. Karamlou, B. W. McCrindle, and C. A. Caldarone Management options in neonates and infants with critical left ventricular outflow tract obstruction Eur. J. Cardiothorac. Surg., June 1, 2007; 31(6): 1013 - 1021. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Mitani, S. Takabayashi, H. Sawada, H. Ohashi, H. Hayakawa, Y. Ikeyama, K. Imanaka-Yoshida, K. Maruyama, H. Shimpo, and Y. Komada Fate of the "opened" arterial duct: Lessons learned from bilateral pulmonary artery banding for hypoplastic left heart syndrome under the continuous infusion of prostaglandin E1 J. Thorac. Cardiovasc. Surg., June 1, 2007; 133(6): 1653 - 1654. [Full Text] [PDF] |
||||
![]() |
T.-J. Yun, W.-C. Cho, S.-H. Jung, D.-M. Seo, H.-W. Goo, and Y.-H. Kim Reverse Blalock-Taussig Shunt Facilitates the Growth of the Ascending Aorta After Hybrid Palliation Ann. Thorac. Surg., May 1, 2007; 83(5): 1886 - 1888. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Khairy, N. Poirier, and L.-A. Mercier Univentricular Heart Circulation, February 13, 2007; 115(6): 800 - 812. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Alsoufi, J. Bennetts, S. Verma, and C. A. Caldarone New Developments in the Treatment of Hypoplastic Left Heart Syndrome Pediatrics, January 1, 2007; 119(1): 109 - 117. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. D. Myers, J. H. Boyd, R. G. Presson Jr, P. Vijay, A. C. Coats, J. W. Brown, and M. D. Rodefeld Neonatal Cavopulmonary Assist: Pulsatile Versus Steady-Flow Pulmonary Perfusion Ann. Thorac. Surg., January 1, 2006; 81(1): 257 - 263. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. D. Myers, K. Mattix, R. G. Presson Jr, P. Vijay, D. Maynes, K. N. Litwak, J. W. Brown, and M. D. Rodefeld Twenty-Four Hour Cardiopulmonary Stability in a Model of Assisted Newborn Fontan Circulation Ann. Thorac. Surg., January 1, 2006; 81(1): 264 - 271. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. A. Bacha, S. Daves, J. Hardin, R.-i. Abdulla, J. Anderson, M. Kahana, P. Koenig, B. N. Mora, M. Gulecyuz, J. P. Starr, et al. Single-ventricle palliation for high-risk neonates: The emergence of an alternative hybrid stage I strategy J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 163 - 171. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Takabayashi, H. Shimpo, Y. Ozu, K. Yokoyama, and M. Kajimoto A Fontan completion through stage I bilateral pulmonary artery banding for hypoplastic left heart syndrome J. Thorac. Cardiovasc. Surg., November 1, 2005; 130(5): 1464 - 1465. [Full Text] [PDF] |
||||
![]() |
C. A. Caldarone, L. N. Benson, H. Holtby, and G. S. Van Arsdell Main pulmonary artery to innominate artery shunt during hybrid palliation of hypoplastic left heart syndrome J. Thorac. Cardiovasc. Surg., October 1, 2005; 130(4): e1 - e2. [Full Text] [PDF] |
||||
![]() |
S. Takabayashi, H. Shimpo, M. Kajimoto, K. Yokoyama, H. Kado, and Y. Mitani Stage I bilateral pulmonary artery banding maintains systemic flow by prostaglandin E1 infusion or a main pulmonary artery to the descending aorta shunt for hypoplastic left heart syndrome Interactive CardioVascular and Thoracic Surgery, August 1, 2005; 4(4): 352 - 355. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. N. Fenton, R. D. Siewers, B. Rebovich, and F. A. Pigula Interim mortality in infants with systemic-to-pulmonary artery shunts Ann. Thorac. Surg., July 1, 2003; 76(1): 152 - 156. [Abstract] [Full Text] [PDF] |
||||
![]() |
I Michel-Behnke, H Akintuerk, I Marquardt, M Mueller, J Thul, J Bauer, K J Hagel, J Kreuder, P Vogt, and D Schranz Stenting of the ductus arteriosus and banding of the pulmonary arteries: basis for various surgical strategies in newborns with multiple left heart obstructive lesions Heart, June 1, 2003; 89(6): 645 - 650. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. B. Mitchell, D. N. Campbell, M. M. Boucek, H. M. Sondheimer, K. C. Chan, D. D. Ivy, B. Pietra, and T. Mackenzie Mechanical limitation of pulmonary blood flow facilitates heart transplantation in older infants with hypoplastic left heart syndrome Eur. J. Cardiothorac. Surg., May 1, 2003; 23(5): 735 - 742. [Abstract] [Full Text] [PDF] |
||||
|
Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 2002 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |