This Article Full Text Full Text (PDF) All Versions of this Article: 105/25/3004    most recent 01.CIR.0000019733.56553.D8v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ishii, M. Articles by Kato, H. Search for Related Content PubMed PubMed Citation Articles by Ishii, M. Articles by Kato, H. Pubmed/NCBI databases Medline Plus Health Information Kawasaki Disease Related Collections Catheter-based coronary and valvular interventions: other Catheter-based coronary interventions: stents Coronary imaging: angiography/ultrasound/Doppler/CC CV surgery: coronary artery disease Pediatric and congenital heart disease, including cardiovascular surgery

(Circulation. 2002;105:3004.)
© 2002 American Heart Association, Inc.

Clinical Investigation and Reports

Sequential Follow-Up Results of Catheter Intervention for Coronary Artery Lesions After Kawasaki Disease

Quantitative Coronary Artery Angiography and Intravascular Ultrasound Imaging Study

Masahiro Ishii, MD^*; Takafumi Ueno, MD^*; Hisao Ikeda, MD; Motofumi Iemura, MD; Tetsu Sugimura, MD; Jun Furui, MD; Yoko Sugahara, MD; Hiromi Muta, MD; Teiji Akagi, MD; Yuichi Nomura, MD; Tomoki Homma, MD; Hiroyoshi Yokoi, MD; Masakiyo Nobuyoshi, MD; Toyojiro Matsuishi, MD; Hirohisa Kato, MD

From the Department of Pediatrics and the Cardiovascular Research Institute (M. Ishii, M. Iemura, T.S., J.F., Y.S., H.M., T.A., H.K.) and Department of Internal Medicine III (T.U., H.I., T.H.), Kurume University School of Medicine, Kurume, Japan; Department of Pediatrics (Y.N.), Kagoshima University School of Medicine, Kagoshima, Japan; and Department of Cardiology (H.Y., M.N.), Kokura Memorial Hospital, Kokura, Japan.

Correspondence to Masahiro Ishii, MD, Kurume University School of Medicine, Department of Pediatrics, 67 Asahi-machi, Kurume 830, Japan. E-mail masaishi{at}med.kurume-u.ac.jp

Background— The purpose of this study was to assess the sequential follow-up results of catheter intervention in Kawasaki disease by use of quantitative coronary angiography (QCA) and intravascular ultrasound imaging.

Methods and Results— Catheter intervention was performed on 23 stenotic lesions in 22 patients (aged 2 to 24 years). Percutaneous balloon angioplasty (PBA) was performed in 4 patients, stent implantation in 7, percutaneous transluminal coronary rotational ablation (PTCRA) in 10, and a combination of PTCRA with stent implantation in 2. A total of 21 lesions (91%) were successfully dilated by catheter intervention without major or minor complications. One patient immediately underwent coronary artery bypass grafting (CABG) surgery because stent implantation failed to resolve his lesion. At 4 to 6 months after catheter intervention, 2 restenotic lesions (9%) were detected by QCA in 2 patients who had undergone PBA, and these patients subsequently underwent CABG surgery. In 6 months to 3 years after catheter intervention, no patients showed evidence of ischemic findings. At 3 to 4 years after catheter intervention, QCA and intravascular ultrasound studies were performed on 15 lesions in 14 patients. Two restenotic lesions (13%) were detected by QCA in 2 patients. One of the 2 had stent implantation and underwent CABG surgery, and the other had undergone PTCRA and underwent re-PTCRA. Thirteen patients demonstrated no ischemic findings at 3 to 8 years after catheter intervention.

Conclusion— Catheter intervention for Kawasaki disease can be accomplished and can be effective in the short term, but the long-term efficacy should be verified by further study.

Key Words: angioplasty • balloon • pediatrics

This article has been cited by other articles:

				J. B. Gordon, A. M. Kahn, and J. C. Burns When children with kawasaki disease grow up myocardial and vascular complications in adulthood. J. Am. Coll. Cardiol., November 17, 2009; 54(21): 1911 - 1920. [Abstract] [Full Text] [PDF]

				S. Kitamura, E. Tsuda, J. Kobayashi, H. Nakajima, Y. Yoshikawa, T. Yagihara, and A. Kada Twenty-Five-Year Outcome of Pediatric Coronary Artery Bypass Surgery for Kawasaki Disease Circulation, July 7, 2009; 120(1): 60 - 68. [Abstract] [Full Text] [PDF]

				L E Wood and R M R Tulloh Kawasaki disease in children Heart, May 1, 2009; 95(10): 787 - 792. [Abstract] [Full Text] [PDF]

				J. D. Pruetz, M. Takahashi, B. L. Reemtsen, and V. A. Starnes A novel surgical approach to left main coronary artery giant aneurysm thrombosis in a child with a history of Kawasaki disease J. Thorac. Cardiovasc. Surg., April 1, 2009; 137(4): 1030 - 1032. [Full Text] [PDF]

				H. Senzaki Long-Term Outcome of Kawasaki Disease Circulation, December 16, 2008; 118(25): 2763 - 2772. [Full Text] [PDF]

				J. W. Newburger, M. Takahashi, M. A. Gerber, M. H. Gewitz, L. Y. Tani, J. C. Burns, S. T. Shulman, A. F. Bolger, P. Ferrieri, R. S. Baltimore, et al. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association Pediatrics, December 1, 2004; 114(6): 1708 - 1733. [Abstract] [Full Text] [PDF]

				J. W. Newburger, M. Takahashi, M. A. Gerber, M. H. Gewitz, L. Y. Tani, J. C. Burns, S. T. Shulman, A. F. Bolger, P. Ferrieri, R. S. Baltimore, et al. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association Circulation, October 26, 2004; 110(17): 2747 - 2771. [Abstract] [Full Text] [PDF]

				J. J Jang, J. W Olin, and V. Fuster A teenager with mixed connective tissue disease presenting with an acute coronary syndrome Vascular Medicine, February 1, 2004; 9(1): 31 - 34. [Abstract] [PDF]