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(Circulation. 1999;100:II-224.)
© 1999 American Heart Association, Inc.

Thoracic Transplantation and Ventricular Assist Devices

Ambulatory Care of Patients With Left Ventricular Assist Devices

Christof Schmid, MD; Dieter Hammel, MD; Mario C. Deng, MD; Michael Weyand, MD; Hideo Baba, MD; Tonny D. T. Tjan, MD; Gabriele Drees, MD(P); Norbert Roeder, MD; Christoph Schmidt, MD; Hans H. Scheld, MD

From the Department of Cardiothoracic Surgery (C.S., D.H., M.C.D., M.W., T.D.T.T., G.D., N.R., H.H.S.), Gerhardt Domagk Institute of Pathology (H.B.), and the Department of Anesthesiology and Intensive Care Medicine (C.S.), University of Münster, Münster, Germany.

Correspondence to PD Dr Christof Schmid, Klinik und Poliklinik für Thorax-, Herz- und Gefässchirurgie, Albert-Schweitzer-Str 33, 48149 Münster, Germany. E-mail schmid{at}uni-muenster.de

Background—Left ventricular assist devices (LVAD) have revolutionized the treatment of patients with acute and chronic heart failure as they provide a high quality of life. We report on our experience with patients receiving ambulatory care after LVAD implantation.

Methods and Results—Since July 1995, 46 patients with a mean age of 45±11 years underwent implantation of an electrically driven LVAD with portable controller and batteries. Sixteen (35%) patients bridged >30 days were treated in part on an outpatient basis. After LVAD implantation, they were treated in the hospital for 86±32 days (range 40 to 153 days). Afterward, they received ambulatory care for 74±76 days (range 2 to 301 days, total experience 1206 days). In 13 cases, the outpatient treatment was interrupted by 1.7±1.7 readmissions, for a total of 32±42 days (median 19 days). Reasons for readmission included systemic or drive line infections (incidence 0.0066 per outpatient day), suspected or true thromboembolic events (incidence 0.0066 per outpatient day), and suspected malfunction of the LVAD. One patient supported as alternative to transplantation died after cerebral bleeding after 244 days, 1 patient with a history of acute myocarditis had ventricular fibrillation during LVAD assist while being at home for 177 days and died in a low output state, 10 patients were given transplantation after a mean support interval of 206±88 days, and 4 patients currently await heart transplantation.

Conclusions—Outpatient treatment after LVAD implantation is feasible, and severe complications are uncommon.

Key Words: cardiomyopathy • heart failure • transplantation