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(Circulation. 1999;100:II-151.)
© 1999 American Heart Association, Inc.

Surgery for Congenital Heart Disease

Effect of Accessory Pulmonary Blood Flow on Survival After the Bidirectional Glenn Procedure

Richard D. Mainwaring, MD; John J. Lamberti, MD; Karen Uzark, PhD; Robert L. Spicer, MD; Mark W. Cocalis, MD; John W. Moore, MD

From the Cardiac Institute, Children’s Hospital–San Diego, San Diego, Calif.

Correspondence to Richard D. Mainwaring, MD, Alfred I. duPont Hospital for Children, Nemours Cardiac Center, 1600 Rockland Rd, Wilmington, DE 19803. E-mail rmainwar{at}nemours.org

Background—The bidirectional Glenn procedure (BDG) is used in the staged surgical management of patients with a functional single ventricle. Controversy exists regarding whether accessory pulmonary blood flow (APBF) should be left at the time of BDG to augment systemic saturation or be eliminated to reduce volume load of the ventricle. The present study was a retrospective review of patients undergoing BDG that was conducted to assess the influence of APBF on survival rates.

Methods and Results—From 1986 through 1998, 149 patients have undergone BDG at our institution. Ninety-three patients had elimination of all sources of APBF, whereas 56 patients had either a shunt or a patent right ventricular outflow tract intentionally left in place to augment the pulmonary blood flow provided by the BDG. The operative mortality rate was 2.2% without APBF and 5.4% with APBF. The late mortality rate was 4.4% without APBF and 15.1% with APBF. Actuarial analysis demonstrates a divergence of the Kaplan-Meier curves in favor of patients in whom APBF was eliminated (P<0.02). One hundred seven patients have subsequently undergone completion of their Fontan operation, so the actuarial analysis includes the operative risk of this second operation.

Conclusions—The results suggest that the elimination of APBF at the time of BDG may confer a long-term advantage for patients with a functional single ventricle.

Key Words: blood flow • Fontan procedure • mortality • morbidity