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(Circulation. 1999;100:361-368.)
© 1999 American Heart Association, Inc.
Clinical Investigation and Reports |
Alterations in the Local Myocardial Motion Pattern in Patients Suffering From Pressure Overload Due to Aortic Stenosis
From the Institute of Biomedical Engineering and Medical Informatics, University and ETH Zurich (M.S., M.B.S., S.E.F., P.B.), and the Department of Internal Medicine, Cardiology, University Hospital (E.N., F.S., O.M.H.), Zurich, Switzerland.
Correspondence to Prof Dr P. Boesiger, Institute of Biomedical Engineering and Medical Informatics, University and ETH Zurich, Gloriastrasse 35, CH-8092 Zurich, Switzerland. E-mail boesiger{at}biomed.ee.ethz.ch
Background—MR tissue tagging allows the noninvasive assessment of the locally and temporally resolved motion pattern of the left ventricle. Alterations in cardiac torsion and diastolic relaxation of the left ventricle were studied in patients with aortic stenosis and were compared with those of healthy control subjects and championship rowers with physiological volume-overload hypertrophy.
Methods and Results—Twelve aortic stenosis patients, 11 healthy control subjects with normal left ventricular function, and 11 world-championship rowers were investigated for systolic and diastolic heart wall motion on a basal and an apical level of the myocardium. Systolic torsion and untwisting during diastole were examined by use of a novel tagging technique (CSPAMM) that provides access to systolic and diastolic motion data. In the healthy heart, the left ventricle performs a systolic wringing motion, with a counterclockwise rotation at the apex and a clockwise rotation at the base. Apical untwisting precedes diastolic filling. In the athlete's heart, torsion and untwisting remain unchanged compared with those of the control subjects. In aortic stenosis patients, torsion is significantly increased and diastolic apical untwisting is prolonged compared with those of control subjects or athletes.
Conclusions—Torsional behavior as observed in pressure- and volume-overloaded hearts is consistent with current theoretical findings. A delayed diastolic untwisting in the pressure-overloaded hearts of the patients may contribute to a tendency toward diastolic dysfunction.
Key Words: magnetic resonance imaging • hypertrophy • stenosis • mechanics
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|
|
|
|
|
|
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|
|
|
|
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|
|
|
 |
|
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|
|
|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
C. Coghlan and J. Hoffman Leonardo da Vinci's flights of the mind must continue: cardiac architecture and the fundamental relation of form and function revisited Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S4 - S17. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. P. Lunkenheimer, K. Redmann, P. Westermann, K. Rothaus, C. W. Cryer, P. Niederer, and R. H. Anderson The myocardium and its fibrous matrix working in concert as a spatially netted mesh: a critical review of the purported tertiary structure of the ventricular mass Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S41 - S49. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. D. Buckberg, M. Castella, M. Gharib, and S. Saleh Structure/function interface with sequential shortening of basal and apical components of the myocardial band Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S75 - S97. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. D. Buckberg, M. Castella, M. Gharib, and S. Saleh Active myocyte shortening during the 'isovolumetric relaxation' phase of diastole is responsible for ventricular suction; 'systolic ventricular filling' Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S98 - S106. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Castella, G. D. Buckberg, and S. Saleh Diastolic dysfunction in stunned myocardium: a state of abnormal excitation-contraction coupling that is limited by Na+-H+ exchange inhibition Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S107 - S114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Chung, P. Abraszewski, X. Yu, W. Liu, A. J. Krainik, M. Ashford, S. D. Caruthers, J. B. McGill, and S. A. Wickline Paradoxical Increase in Ventricular Torsion and Systolic Torsion Rate in Type I Diabetic Patients Under Tight Glycemic Control J. Am. Coll. Cardiol., January 17, 2006; 47(2): 384 - 390. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Helle-Valle, J. Crosby, T. Edvardsen, E. Lyseggen, B. H. Amundsen, H.-J. Smith, B. D. Rosen, J. A.C. Lima, H. Torp, H. Ihlen, et al. New Noninvasive Method for Assessment of Left Ventricular Rotation: Speckle Tracking Echocardiography Circulation, November 15, 2005; 112(20): 3149 - 3156. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. W.W. Biederman, M. Doyle, J. Yamrozik, R. B. Williams, V. K. Rathi, D. Vido, K. Caruppannan, N. Osman, V. Bress, G. Rayarao, et al. Physiologic Compensation Is Supranormal in Compensated Aortic Stenosis: Does it Return to Normal After Aortic Valve Replacement or Is it Blunted by Coexistent Coronary Artery Disease?: An Intramyocardial Magnetic Resonance Imaging Study Circulation, August 30, 2005; 112(9_suppl): I-429 - I-436. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Notomi, P. Lysyansky, R. M. Setser, T. Shiota, Z. B. Popovic, M. G. Martin-Miklovic, J. A. Weaver, S. J. Oryszak, N. L. Greenberg, R. D. White, et al. Measurement of Ventricular Torsion by Two-Dimensional Ultrasound Speckle Tracking Imaging J. Am. Coll. Cardiol., June 21, 2005; 45(12): 2034 - 2041. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Castella, G. D. Buckberg, S. Saleh, and M. Gharib Structure function interface with sequential shortening of basal and apical components of the myocardial band Eur. J. Cardiothorac. Surg., June 1, 2005; 27(6): 980 - 987. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Paetsch, D. Foll, A. Kaluza, R. Luechinger, M. Stuber, A. Bornstedt, A. Wahl, E. Fleck, and E. Nagel Magnetic resonance stress tagging in ischemic heart disease Am J Physiol Heart Circ Physiol, June 1, 2005; 288(6): H2708 - H2714. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Notomi, R. M. Setser, T. Shiota, M. G. Martin-Miklovic, J. A. Weaver, Z. B. Popovic, H. Yamada, N. L. Greenberg, R. D. White, and J. D. Thomas Assessment of Left Ventricular Torsional Deformation by Doppler Tissue Imaging: Validation Study With Tagged Magnetic Resonance Imaging Circulation, March 8, 2005; 111(9): 1141 - 1147. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. P. Lunkenheimer, K. Redmann, and R. H. Anderson The architecture of the ventricular mass and its functional implications for organ-preserving surgery Eur. J. Cardiothorac. Surg., February 1, 2005; 27(2): 183 - 190. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Beller, M. R. Labrosse, M. J. Thubrikar, G. Szabo, F. Robicsek, and S. Hagl Increased aortic wall stress in aortic insufficiency: clinical data and computer model Eur. J. Cardiothorac. Surg., February 1, 2005; 27(2): 270 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Waters, A. W. Bowman, and S. J. Kovacs MRI-determined left ventricular "crescent effect": a consequence of the slight deviation of contents of the pericardial sack from the constant-volume state Am J Physiol Heart Circ Physiol, February 1, 2005; 288(2): H848 - H853. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Marwick, P. A. Kirkham, C. S. Stevenson, H. Danahay, J. Giddings, K. Butler, K. Donaldson, W. MacNee, and I. Rahman Cigarette Smoke Alters Chromatin Remodeling and Induces Proinflammatory Genes in Rat Lungs Am. J. Respir. Cell Mol. Biol., December 1, 2004; 31(6): 633 - 642. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Fuchs, M. F. Muller, H. Oswald, H. Thony, P. Mohacsi, and O. M. Hess Cardiac rotation and relaxation in patients with chronic heart failure Eur J Heart Fail, October 1, 2004; 6(6): 715 - 722. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. D. Rosen, B. L. Gerber, T. Edvardsen, E. Castillo, L. C. Amado, K. Nasir, D. L. Kraitchman, N. F. Osman, D. A. Bluemke, and J. A. C. Lima Late systolic onset of regional LV relaxation demonstrated in three-dimensional space by MRI tissue tagging Am J Physiol Heart Circ Physiol, October 1, 2004; 287(4): H1740 - H1746. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Mishra, A. Chaudhary, and S. Sethi Oxidized Omega-3 Fatty Acids Inhibit NF-{kappa}B Activation Via a PPAR{alpha}-Dependent Pathway Arterioscler Thromb Vasc Biol, September 1, 2004; 24(9): 1621 - 1627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Beller, M. R. Labrosse, M. J. Thubrikar, and F. Robicsek Role of Aortic Root Motion in the Pathogenesis of Aortic Dissection Circulation, February 17, 2004; 109(6): 763 - 769. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ashikaga, J. C. Criscione, J. H. Omens, J. W. Covell, and N. B. Ingels Jr. Transmural left ventricular mechanics underlying torsional recoil during relaxation Am J Physiol Heart Circ Physiol, February 1, 2004; 286(2): H640 - H647. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. H. Mahabeleshwar and G. C. Kundu Tyrosine Kinase p56lck Regulates Cell Motility and Nuclear Factor {kappa}B-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of I{kappa}B{alpha} following Hypoxia/Reoxygenation J. Biol. Chem., December 26, 2003; 278(52): 52598 - 52612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. G. Fonseca, H. C. Oxenham, B. R. Cowan, C. J. Occleshaw, and A. A. Young Aging alters patterns of regional nonuniformity in LV strain relaxation: a 3-D MR tissue tagging study Am J Physiol Heart Circ Physiol, July 11, 2003; 285(2): H621 - H630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Setser, J. M. Kasper, M. L. Lieber, R. C. Starling, P. M. McCarthy, and R. D. White Persistent abnormal left ventricular systolic torsion in dilated cardiomyopathy after partial left ventriculectomy J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 48 - 55. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Van der Toorn, P. Barenbrug, G. Snoep, F. H. Van der Veen, T. Delhaas, F. W. Prinzen, J. Maessen, and T. Arts Transmural gradients of cardiac myofiber shortening in aortic valve stenosis patients using MRI tagging Am J Physiol Heart Circ Physiol, October 1, 2002; 283(4): H1609 - H1615. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.J.W. van Kraaij, P.E.J. van Pol, A.W. Ruiters, J.B.R.M. de Swart, D.J. Lips, N. Lencer, and P.A.F.M. Doevendans Diagnosing diastolic heart failure Eur J Heart Fail, August 1, 2002; 4(4): 419 - 430. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. A. Tibayan, D. T. M. Lai, T. A. Timek, P. Dagum, D. Liang, G. T. Daughters, N. B. Ingels, and D. C. Miller Alterations in left ventricular torsion in tachycardia-induced dilated cardiomyopathy J. Thorac. Cardiovasc. Surg., July 1, 2002; 124(1): 43 - 49. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. J. W. Sandstede, T. Johnson, K. Harre, M. Beer, S. Hofmann, T. Pabst, W. Kenn, W. Voelker, S. Neubauer, and D. Hahn Cardiac Systolic Rotation and Contraction Before and After Valve Replacement for Aortic Stenosis: A Myocardial Tagging Study Using MR Imaging Am. J. Roentgenol., April 1, 2002; 178(4): 953 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N.-S. Chang The Non-ankyrin C Terminus of Ikappa Balpha Physically Interacts with p53 in Vivo and Dissociates in Response to Apoptotic Stress, Hypoxia, DNA Damage, and Transforming Growth Factor-beta 1-mediated Growth Suppression J. Biol. Chem., March 15, 2002; 277(12): 10323 - 10331. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. C. Colombo, A. W. Ashton, S. Celaj, A. Talreja, J. E. Banchs, N. B. Dubois, M. Marinaccio, S. Malla, J. Lachmann, J. A. Ware, et al. Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium J Appl Physiol, March 1, 2002; 92(3): 1331 - 1338. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. POPPAS and S. ROUNDS Congestive Heart Failure Am. J. Respir. Crit. Care Med., January 1, 2002; 165(1): 4 - 8. [Full Text] [PDF]
|
|
|
|
|
|
D J Sahn and G W Vick III Review of new techniques in echocardiography and magnetic resonance imaging as applied to patients with congenital heart disease Heart, December 1, 2001; 86(90002): ii41 - 53. [Full Text] [PDF]
|
|
|
|
 |
|
 E. N. Wardle Nuclear factor {kappa}B for the nephrologist Nephrol. Dial. Transplant., September 1, 2001; 16(9): 1764 - 1768. [Full Text] [PDF]
|
|
|
|
|
|
S. B. Yeon, N. Reichek, B. A. Tallant, J. A. C. Lima, L. P. Calhoun, N. R. Clark, E. A. Hoffman, K. K. L. Ho, and L. Axel Validation of in vivo myocardial strain measurement by magnetic resonance tagging with sonomicrometry J. Am. Coll. Cardiol., August 1, 2001; 38(2): 555 - 561. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
K. Rajappan, N. G. Bellenger, L. Anderson, and D. J. Pennell The role of cardiovascular magnetic resonance in heart failure Eur J Heart Fail, September 1, 2000; 2(3): 241 - 252. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Fogel, P. M. Weinberg, A. Hubbard, and J. Haselgrove Diastolic Biomechanics in Normal Infants Utilizing MRI Tissue Tagging Circulation, July 11, 2000; 102(2): 218 - 224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
H. M. Spotnitz Macro design, structure, and mechanics of the left ventricle J. Thorac. Cardiovasc. Surg., May 1, 2000; 119(5): 1053 - 1077. [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
R. E. Henson, S. K. Song, J. S. Pastorek, J. J. H. Ackerman, and C. H. Lorenz Left ventricular torsion is equal in mice and humans Am J Physiol Heart Circ Physiol, April 1, 2000; 278(4): H1117 - H1123. [Abstract] [Full Text] [PDF]
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J. Garot, D. A. Bluemke, N. F. Osman, C. E. Rochitte, E. R. McVeigh, E. A. Zerhouni, J. L. Prince, and J. A. C. Lima Fast Determination of Regional Myocardial Strain Fields From Tagged Cardiac Images Using Harmonic Phase MRI Circulation, March 7, 2000; 101(9): 981 - 988. [Abstract] [Full Text] [PDF]
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 L. Mandinov, F. R. Eberli, C. Seiler, and O. M. Hess Diastolic heart failure Cardiovasc Res, March 1, 2000; 45(4): 813 - 825. [Abstract] [Full Text] [PDF]
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