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Figure 1. Effect of Ad-APN treatment on atherosclerotic lesions in apoE-/- mice 14 days after recombinant adenovirus injection. A, The representative lesions before and after injection of Ad-ßgal or Ad-APN (n=9 each) with low (A, bar=500 µm) and high (C, bar=100 µm) magnification are shown. B, Quantification of lesion areas in each group. The average lesion area of each mouse was determined from 3 cross-sections (100 µm apart). D, The diameter of lipid droplets over 10 µm in Ad-ßgal or Ad-APN treated mice (n=9 each). The values are mean±SEM.